Bovine tuberculosis

v

Preface vii

Contributors ix

List of figures xii

1 Bovine Tuberculosis: Worldwide Picture 1

Lina Awada, Paolo Tizzani, Elisabeth Erlacher-Vindel, Simona Forcella and Paula Caceres

2 Mycobacterium bovis as the Causal Agent of Human Tuberculosis:

Public Health Implications 16

Francisco Olea-Popelka, Anna S. Dean, Adrian Muwonge, Alejandro Perera, Mario Raviglione

and Paula I. Fujiwara

3 Economics of Bovine Tuberculosis: A One Health Issue 31

Hind Yahyaoui Azami and Jakob Zinsstag

4 The Epidemiology of Mycobacterium bovis Infection in Cattle 43

Andrew J.K. Conlan and James L.N. Wood

5 Mycobacterium bovis Molecular Typing and Surveillance 58

Robin A. Skuce, Andrew W. Byrne, Angela Lahuerta-Marin and Adrian Allen

6 Bovine Tuberculosis in Other Domestic Species 80

Anita L. Michel

7 Role of Wildlife in the Epidemiology of Mycobacterium bovis 93

Naomi J. Fox, Paul A. Barrow and Michael R. Hutchings

8 Molecular Virulence Mechanisms of Mycobacterium bovis 106

Alicia Smyth and Stephen V. Gordon

Contents