Machine Design – May 2019

(Frankie) #1

“In some scenarios, such as nature
scenes, people didn’t mind if the trees
were a little different or the giraffe was a dif-
ferent giraffe; they cared more about them
not being blurry, which means traditional
computer compression ranked lower,”
says researcher Shubham Chandak. “But
for human faces, people would rather have
the same face even if it’s blurry.”
This apparent weakness in human-
based image sharing would improve as
more people upload images of themselves
to the internet. The researchers are also
teaming with a police sketch artist to see
how his expertise might make a difference.
Even though this work shows the value of
human input, the researchers would even-
tually try to automate the process.
“Machine learning is working on bits and
parts of this, and hopefully we can get them
working together soon,” says researcher
Kedar Tatwawadir. “It seems like a practical
compressor that works with this kind of
ideology is not very far away.” 


News

IDENTIFYING CANCER CELL TYPES in a Hurry


FOR DOCTORS TO determine the best
treatment for cancer patients, they must
know what types of cancer cells they are
dealing with, which is not an easy task.
Even within the same tumor, for example,
cancer cells can differ in their genetics,
behavior, and susceptibility to chemother-
apy drugs.
Cancer cells are generally much more
metabolically active than healthy cells, so

some insight into a cancer cell’s behavior
and type can be gathered by analyzing
its metabolic activity. But getting an ac-
curate assessment of metabolic activity
has proven difficult. Several methods, in-
cluding position emission tomography (or
PET) scans, fluorescent dyes, and con-
trast agents have been used, but each is
limited it is usefulness.
According to a medical and electrical
engineering professor at Caltech, Lihong
Wang, photoacoustic microscopy (PAM)
would help in identifying cancer cells. It
uses a laser to induce ultrasonic vibra-
tions in samples. Those vibrations can
image cells, blood vessels, and tissues.
Wang is using PAM to improve an existing
technology for measuring cells’ oxygen-
consumption rate (OCR).
OCR takes many cancer cells, each in
a container filled with blood. Cells with
higher metabolisms use up more oxygen

22


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MAY 2019 MACHINE DESIGN
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