THE PHYSICAL BRAIN
Nerve Signals
FLUID INSIDE AXON
Direction of nerve
impulse
Nerve Signals
The brain and nervous system work by sending
signals through cells as pulses of electrical
charge and between cells either by using
chemical messengers called neurotransmitters
or by electric charge.
Action potential
Neurons signal by creating an action potential—a surge of
electricity created by sodium and potassium ions crossing
the cell’s membrane. It travels down the axon and
stimulates receptors on dendrites of neighboring cells.
The junction between cells is called a synapse. In many
neurons, the charge is carried over a minute gap between
axon and dendrite by chemicals, called neurotransmitters,
released from the tip of the axon. These junctions are
known as chemical synapses. The signal may cause the
neighboring neuron to fire, or it may stop it from firing.
Membrane channels
open to let ions in
HOW DOES A
NERVE COMMUNICATE
DIFFERENT INFORMATION?
Receiving cells have different
types of receptors, which respond
to different neurotransmitters.
The “message” differs according
to which neurotransmitters
are sent and received and
in what quantities.
Depolarization
Chemical changes from the cell body
allow positive ions to flood into the cell
through the membrane. That reverses the
polarization of the axon, making the
potential difference +30 millivolts.
Resting potential
When the neuron is at rest, there are more positive
ions outside the membrane than inside. This causes a
difference in polarization, or electrical potential, across
the membrane called the resting potential. The difference
is about –70 millivolts, meaning the outside is positive.
SOME NERVE IMPULSES
TRAVEL FASTER THAN
330 F T (100 M) PER
SECOND
CELL’S AXON MEMBRANE
Excess of ions inside
produces a positive charge
Excess of positive ions on
outside of cell membrane
KEY
Direction of
nerve impulse
Flow of ions
Positive ions
rush in
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