THE PHYSICAL BRAIN
Networks in the Brain
Networks
in the Brain
The patterns of nerve-cell connections in the
human brain are believed to influence how
it processes sensory perceptions, performs
cognitive tasks, and stores memories.
Wiring the brain
The dominant theory of how the brain remembers
and learns can be summed up by the phrase “the
cells that fire together, wire together.” It suggests
that repeated communication between cells creates
stronger connections between them, and a network
of cells emerges in the brain that is associated with
a specific mental process—such as a movement,
a thought, or even a memory (see pp.136–37).
Weak
synapses
KEY
Glutamate
neurotransmitter
Magnesium
ion
Calcium ion
Channel
Glutamate
receptor
Channel blocked
In a weak connection, magnesium ions block
the passage of calcium ions into the dendrite of a
receiving neuron. A glutamate neurotransmitter
received from the axon will open that channel.
1
Neuroplasticity
The networks of the brain are not
fixed but seem to change and adapt
in accordance with mental and
physical processes. This means
that old circuits associated with
one memory or a skill that is no
longer in use fade in strength as
the brain devotes attention to
another and forms a new network
with other cells. Neuroscientists
say the brain is plastic, meaning its
cells and the connections between
them can be reformed many times
over as required. Neuroplasticity
allows brains to recover abilities
lost due to brain damage.
Synaptic weight
Little-used connections
have channels blocked
by magnesium ions. As the
strength of a connection
between two neurons in
a network increases, the
channel is unblocked, and
the number of receptors
at the synapse increases.
BRAIN PATHWAYS
Strong
synapses
Magnesium ion
blocks channel
Calcium unable
to access channel
DENDRITE
SYNAPTIC CLEFT
AXON
Glutamate
neurotransmitter
binds to receptor,
eventually causing
channel to unblock
Axon releases
glutamate
neurotransmitter
Calcium ions
facilitate signaling
between neurons
WHAT IS THE BRAIN’S
DEFAULT MODE NETWORK?
It is a group of brain regions
that show low activity levels
when engaged in a task such
as paying attention but high
activity levels when awake and
not engaged in a specific
mental task.
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