THE PHYSICAL BRAIN
Nuclei of the Brain
Nuclei of
the Brain
In brain anatomy, a nucleus is a cluster
of nerve cells that have a discernible set
of functions and are connected to each
other by tracts of white matter.
The basal ganglia and other nuclei
An important group of nuclei collectively known
as the basal ganglia sit within the forebrain and
have strong links with the thalamus and brain
stem. They are associated with learning,
motor control, and emotional responses. All
cranial nerves connect to the brain at a
nucleus (often two: one for sensory inputs
and another for motor outputs). Other
brain nuclei include the hypothalamus
(see p.34), hippocampus (see pp.38–39),
pons, and medulla (see p.36).
Central location
Most of the basal ganglia are
positioned at the base of the forebrain
around the thalamus. The nuclei sit
within a region filled with white-
matter tracts called the striatum.
Nuclei structure
Nuclei are clusters of gray matter (nerve
cell bodies) situated within the brain’s white
matter (nerve axons). Most nuclei do not
have a membrane so, to the naked eye,
seem to blend into the surrounding tissues.
C AUDATE
NUCLEUS TAIL
C AUDATE
NUCLEUS TAIL
C AUDATE
NUCLEUS
WHITE
MAT TER
WHITE
MAT TER
C AUDATE
NUCLEUS
SUBTHALAMIC
NUCLEUS
SUBSTANTIA
NIGRA
AMYGDALA
THALAMUS
GLOBUS
PALLIDUS
Subthalamic
nucleus
Globus
pallidus
Nuclei of amygdala
have been classified
as part of basal
ganglia by some
scientists
Each nucleus
develops as a
mirrored pair,
one in each
hemisphere
Substantia nigra in
midbrain linked with
fine motor control
Caudate
nucleus
Substantia
nigra
FR
O
NT
SL
ICE
RE
AR
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LI
C
E
PU
TA
M
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N
PA
LL
ID
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GL
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