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At the neuromuscular junction, the end
of the axon releases acetylcholine, a
neurotransmitter (see p.24). The acetylcholine
binds to receptors in the muscle cell
membrane. This triggers chemical
reactions that make the muscle
fiber contract.
The upper and lower motor neurons meet in the ventral horn of the spinal cord.
The outer part of the ventral horn carries
nerves that run to the hands and feet;
the central part carries nerves to
the upper arms and thighs.
BRAIN FUNCTIONS AND THE SENSES
Making a Move
From spine to muscleInside the spinal cord, the axons of the corticospinal tract, which are covered with a myelin sheath, form the white matter. The gray matter at the center of the spinal cord consists of the cell bodies of motor neurons. The ends of the corticospinal axons (known as upper motor neurons) synapse on to motor neurons (known as lower motor neurons) in the ventral horn of the gray matter. The axons of the lower neurons exit the spine through gaps in the vertebrae (see p.12) and extend to the muscle fibers. The point where the nerve endings activate the muscle fibers to complete the movement is called the neuromuscular junction.
Upper motor neurons
SP
IN
AL
CO
RD
Executing movementNerve signals make a muscle
contract and pull on the associated joint to move the part of the limb
just beyond it. Muscles used in fine movements have more nerve endings than those used for simple movements.
MUSCLE
HOW LONG DOES IT
TAKE FOR A SIGNAL
TO TRAVEL FROM
BRAIN TO MUSCLE?
Signals can travel
from the brain to our
muscles at a speed of up
to 395 ft (120 m)
per second.
RADIAL NERVE
WHITE MAT TER
GR AY
MAT TER
Acetylcholine
Muscle contracts and moves joint,
causing arm to
bend
AXON TERMINAL
2
3
MUSCLE FIBER
Receptor for acetylcholine
SYNAPTIC CLEFT
Lower motor neurons
RIGHT ARM
Lower motor neurons pass signals from spinal cord to muscles
VENTRAL
HORN
Direction
of signal
US_098_099_Making_a_move.indd 99 20/09/2019 12:35