Nature - USA (2019-07-18)

(Antfer) #1

Letter reSeArCH


Extended Data Fig. 4 | scSLAM-seq differentiates incoming virion-
associated RNA from de novo transcribed viral RNA. Heat maps
showing the levels of old (left) and new (right) RNA relative to the
maximal total level for each viral gene (rows) per CMV-infected cell
(columns). Cells are sorted according to the percentage of viral reads
among all reads from the cell. Kinetic classes are indicated. E, early; IE,
immediate early; L, late; ND, not defined. The ratio of new to old RNA
(log 2 (new/old)) and total expression from pooled cells for each viral gene
are depicted.

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