Article
Extended Data Fig. 8 | Silencing higher visual areas reduces surround
suppression in V1. a, Experimental configuration. A laser beam is scanned
over HVAs around V1 for optogenetic silencing while recording in V1.
b, Size-tuning function of an example unit (baseline subtracted firing rates) to
classical stimuli with (blue) or without (black) HVA silencing. Note the relief of
surround suppression at larger stimulus sizes upon silencing HVAs. c, Scatter
plot of the classical suppression index with or without silencing of HVAs
(Methods). Two-sided Wilcoxon signed-rank test; P = 0.033; 34 units in 12 mice.
Closed and open symbols are units from L2/3 and L5/6, respectively. The green
symbol represents the example unit shown in b. Data are mean ± s.e.m.