Article
Extended Data Table 3 | Detailed description of the case composition for the reader study
Row DescriptionNo.
cancer
casesNo. biopsied
negative
casesNo.
normal
casesTotal Figure(^1) 27-month outcome inclusion based on 125 125 250 500 -
2 manual quality review 113 119 233 465 Figure 3a,b
3 restrict to cancers in 12 months (^56 119 233 408) Extended Data FiFigure 3c gure 2
4 obtain ground truth localizations 53 119 233 405 Extended Data Figure 3
Row 1: 500 cases were selected for the reader study. The case mixture was enriched for positives as well as challenging negatives. Row 2: cases containing breast implants and those for which
at least half of the readers indicated image-quality concerns were excluded from analysis. The remaining 465 cases are represented in Fig. 3a, b. Row 3: for further analysis, we restricted the
cancers to those that developed within 12 months. Cases in which cancer developed later (but within 27 months) were excluded because they did not meet the follow-up criteria to be consid-
ered negative. The remaining 408 cases are represented in Fig. 3c and Extended Data Fig. 2. Row 4: to perform localization analysis, the areas of malignancy were determined using follow-up
biopsy data. In three instances, ground truth could not reliably be determined. The remaining 405 cases are represented in Extended Data Fig. 3.