108 | Nature | Vol 577 | 2 January 2020
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© The Author(s), under exclusive licence to Springer Nature Limited 2019
(^1) The Walter and Eliza Hall Institute, Parkville, Victoria, Australia. (^2) Department of Medical
Biology, University of Melbourne, Parkville, Victoria, Australia.^3 Inflammatory Disease Section,
National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
(^4) Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research,
Clayton, Victoria, Australia.^5 Department of Molecular and Translational Science, Monash
University, Clayton, Victoria, Australia.^6 Light Imaging Section, Office of Science and
Technology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National
Institutes of Health, Bethesda, MD, USA.^7 Translational Immunology Section, National Institute
of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda,
MD, USA.^8 Department of Laboratory Medicine, Clinical Center, National Institutes of Health,
Bethesda, MD, USA.^9 Translational Vascular Medicine Branch, National Heart, Lung, and Blood
Institute, National Institutes of Health, Bethesda, MD, USA.^10 Institute for Genetics & Cologne
Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD),
University of Cologne, Cologne, Germany.^11 Center for Molecular Medicine (CMMC),
University of Cologne, Cologne, Germany.^12 Molecular Development of the Immune System
Section, Laboratory of Immune System Biology; Clinical Genomics Program, National
Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
(^13) Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and
Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.^14 NIH
Intramural Sequencing Center, National Human Genome Research Institute, National
Institutes of Health, Bethesda, MD, USA.^15 Division of Rheumatology, Department of Medicine,
University of California San Francisco, San Francisco, CA, USA.^16 Division of Pulmonary and
Critical Care, Department of Medicine, University of California San Francisco, San Francisco,
CA, USA.^17 These authors contributed equally: Najoua Lalaoui, Steven E. Boyden, Hirotsugu
Oda.^18 These authors jointly supervised this work: Daniel L. Kastner, John Silke. *e-mail:
[email protected]; [email protected]; [email protected];
[email protected]