Nature - USA (2020-08-20)

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Article


Extended Data Fig. 4 | IFNγ and TNF production prof ile of SARS-CoV-2-
specif ic T cells of patients who recovered from COVID-19. PBMCs from
patients recovered from COVID-19 (n = 7) were stimulated with the peptide
pools covering N (NP-1, NP-2) for 5 h and analysed by intracellular cytokine
staining for IFNγ and TNF. Dot plots show examples of patients with CD8 (top)


or CD4 (bottom) T cells that produced IFNγ and/or TNF in response to
stimulation with N-1 or N-2 peptide pools. The bars show the respective single
and double cytokine producing T cells as a proportion of the total detected
response after stimulation with the corresponding N peptide pools in each
patient who recovered from COVID-19.
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