Nature - USA (2020-08-20)

a

b

c

d

present study:

Lipid A modeled

at IFD

1-P

4’-P

KDO

red: Fo-Fc (w CL2) -3σ

blue: Fo-Fc (w CL2) -4σ

green: Fo-Fc (no CL2) 4σ

superimposed onto

6V8Q, chain B

red: Fo-Fc (w CL2) -3σ

blue: Fo-Fc (w CL2) -4σ

green: Fo-Fc (no CL2) 7.5σ superimposed onto

6V8Q, chain B

superimposed onto

6V8Q, chain B

green: Fo-Fc (no CL2) 3σ green: Fo-Fc (no CL2) 3σ

PDB 6V8Q:

CL (CL2) modeled

at IFD, chain A

PDB 6V8Q:

CL (CL2) modeled

at IFD, chain B

P1 P1

P2

P2

Extended Data Fig. 9 | See next page for caption.