PHOTO: GERRY ELLIS/MINDEN PICTURES
SCIENCE sciencemag.org 25 SEPTEMBER 2020 • VOL 369 ISSUE 6511 153925 SEPTEMBER 2020 • VOLUME 369 • ISSUE 65111558
Costa Rica’s biodiversity
has been a magnet
for outside scientists.NEWS
IN BRIEF
1548 News at a glanceIN DEPTH
1550 Flawed interferon response
spurs severe illness
Antibodies or mutations that cripple key
antivirus protein underlie 14% of severe cases
By M. Wadman
RESEARCH ARTICLE BY Q. ZHANG ET AL.
DX.DOI.ORG/10.1126/SCIENCE.ABD4570;
RESEARCH ARTICLE BY P. BASTARD ET AL.
DX.DOI.ORG/10.1126/SCIENCE.ABD1551 Fighting to be counted
The pandemic has fueled Abigail Echo-Hawk’s
quest for health data on Indigenous people in
the United States By L. Wade1553 Despite obstacles, WHO unveils plan
to distribute vaccine
Nations with nearly two-thirds of world’s
population have joined, but not the United
States, Russia, or China By K. Kupferschmidt1554 Turkey targets critics
of its pandemic response
Researchers and physicians who question data
or policies face lengthy investigations
B y K. M cT i g h e1555 Curved scour marks trace the
directions of ancient quakes
“Slickenlines” etched in rocks could help
refine shaking hazard for cities near the ends
of faults B y P. Vo o s e n1565 The last pieces of a puzzling
early meeting
Y chromosomes transferred from Homo
sapiens to Neanderthals between 350,000 to
150,000 years ago By M. H. Schierup
REPORT p. 16531567 Birds do have a brain cortex—
and think
Like mammals, birds have a pallium that
sustains correlates of consciousness
By S. Herculano-Houzel
RESEARCH ARTICLE p. 1585; REPORT p. 16261568 Intense x-rays can be
(slightly) exciting
Imaging of neutral “survivor” atoms excited
by x-ray blasts fights radiation damage
By T. Pfeifer
REPORT p. 1630POLICY FORUM
1570 Self-experimentation, ethics,
and regulation of vaccines
DIY COVID-19 vaccines raise legal and ethical
questions By C. J. Guerrini et al.BOOKS E T AL.
1573 Understanding quantum
cause and effect
Correlations at a distance needn’t necessarily
be “spooky” By A. Stairs1574 The race to decipher
Egyptian hieroglyphs
A pair of scholars recount the rivalry that
defined efforts to interpret the Rosetta stone
By A. Robinson1556 The short, strange life
of quantum radar
In spite of military interest, quantum
mechanics won’t defeat stealth
technologies By A. Cho1557 Sizing up a green carbon sink
Studies zero in on forests’ potential to fight
warming By G. PopkinFEATURES
1558 Seeking a niche
Costa Rica is producing a new generation
of skilled tropical biologists. But many can’t
find jobs at home By J. Kaiser
1561 A tropical research treasure
faces difficult times By J. KaiserCONTENTS
INSIGHTS
PERSPECTIVES
1562 Transformative tools
for parasitic flatworms
Schistosome single-cell atlas and
genome-wide functional dissection
reveal druggable targets
By T. J. C. Anderson and M. T. Duraisingh
REPORTS pp. 1644 & 16491564 Preventing pores and
inflammation
Metabolite-directed modification of
pore-forming cell death protein limits
inflammation By R. J. Pickering and C. E. Bryant
REPORT p. 1633