124 ❯ STEP 4. Review the Knowledge You Need to Score High
Large ribosomal subunit mRNA
A site
(b)
Small ribosomal subunit tRNA ♦To start, the P site lies over the AUG codon of the mRNA and
P site the tRNA carrying the appropriate amino acids binds to the site.
(a) The tRNA carrying the next amino acid arrives at the A site.
Random amino acids
(c)
(f)
(e)
♦This process continues until the stop codon is reached and the
protein is complete.
AUG CGG
♦A peptide bond forms between the two amino acids. The amino
acid from the P site hops onto the A site amino acid, freeing the
tRNA in the P site to leave and find another amino acid to carry.
(d)
Old P site
New P site New A site
Translocation: The ribosome slides along the mRNA in such a
way that the A site becomes the new P site, and the next tRNA
comes into the new A site carrying the next amino acid.
Figure 11.6 A pictorial representation of translation.