Extended Data Fig. 9 | Decoupling tension and bending modulus with
flickering analysis. To test our ability to decouple tension and bending
modulus from our data during the f lickering analysis, we took the 20 highest-
tension and the 20 lowest-tension cells from our database and analysed their
f luctuation power spectra, covering a wide enough range of q-values that both
tension and bending moduli can be robustly extracted. a, b, Boxplots for the
tensions and bending moduli of the 20 cells with extreme high and 20 with
extreme low tensions. Although there is an obvious significant difference in
tension (P = 4.0302 × 10−1 3; two-sided Mann–Whitney U-test), the bending
moduli are similar. c, This is also evident from the overlapping of the two
spectra for the high modes, where a bending-dominated regime prevails,
although the divergence of the f luctuation amplitudes between the two spectra
becomes noticeable when tension predominates. Each mean square fluctuation
spectrum is obtained by averaging all 20 f luctuation spectra for both low-tension
(blue) and high-tension (yellow) cells. As tension dominates low modes
(q−1 behaviour) and bending modulus dominates high modes of the spectra
(q−3 trend), the decoupling between tension and bending modulus becomes
evident from these two spectra (Supplementary Information Section S2).