▶ORif history of immediate hypersensitivity reaction
(including anaphylaxis, angioedema, urticaria, or rash
immediately after administration) to penicillin or to
cephalosporins
Chloramphenicol injection p. 354(1 g)
BY INTRAVENOUS INJECTION
▶Child 1 month–17 years: 12. 5 – 25 mg/kg
NOTEA single dose can be given before urgent transfer to
hospital, so long as this does not delay the transfer.
See also Central nervous system infections, antibacterial
therapy p. 305.Hypoglycaemia
▶DIABETIC HYPOGLYCAEMIA
Glucose or sucrose
BY MOUTH
▶Child over 2 years:approx. 10 – 20 g( 110 – 220 mL
Lucozade®Energy Original or 100 – 200 mL
Coca-Cola®—both non-diet versionsor
2 – 4 teaspoonfuls of sugaror 3 – 6 sugar lumps)
repeated after 10 – 15 minutes if necessary
▶ORif hypoglycaemia unresponsiveorif oral route cannot be
used
Glucagon injection p. 465(1 mg/mL)
BY SUBCUTANEOUS OR INTRAMUSCULAR INJECTION
▶Child body-weight up to 25 kg: 500 micrograms ( 0. 5 mL)
▶Child body-weight 25 kg and over: 1 mg ( 1 mL)▶ORif hypoglycaemia prolongedorunresponsive to glucagon
after 10 minutes
Glucose intravenous infusion p. 590(10%)
BY INTRAVENOUS INJECTION INTO LARGE VEIN
▶Child 1 month–17 years: 5 mL/kg (glucose 500 mg/kg)Seizures
▶CONVULSIVE (INCLUDING FEBRILE) SEIZURES LASTING
LONGER THAN 5 MINUTES
▶EITHERDiazepam rectal solution p. 220(2 mg/mL, 4 mg/mL)
BY RECTUM
▶Neonate: 1. 25 – 2. 5 mg, repeated once after
10 – 15 minutes if necessary
▶Child 1 month–1 year: 5 mg, repeated once after
10 – 15 minutes if necessary
▶Child 2–11 years: 5 – 10 mg, repeated once after
10 – 15 minutes if necessary
▶Child 12–17 years: 10 – 20 mg, repeated once after
10 – 15 minutes if necessary
▶ORMidazolam oromucosal solution p. 223
BY BUCCAL ADMINISTRATION, REPEATED ONCE AFTER 10 MINUTES IF
NECESSARY
▶Neonate: 300 micrograms/kg [unlicensed]
▶Child 1–2 months: 300 micrograms/kg (max. 2. 5 mg)
[unlicensed]
▶Child 3 months–11 months: 2. 5 mg
▶Child 1–4 years: 5 mg
▶Child 5–9 years: 7. 5 mg
▶Child 10–17 years: 10 mg