BNF for Children (BNFC) 2018-2019

(singke) #1
Ceftazidime (as Ceftazidime pentahydrate) 2 gramCeftazidime 2 g
powder for solution for injection vials| 5 vialP£ 79. 15 |
10 vialP£ 27. 70
▶Fortum(GlaxoSmithKline UK Ltd)
Ceftazidime (as Ceftazidime pentahydrate) 500 mgFortum
500 mg powder for solution for injection vials| 1 vialP£ 4. 40
(Hospital only)
Ceftazidime (as Ceftazidime pentahydrate) 1 gramFortum 1 g
powder for solution for injection vials| 1 vialP£ 8. 79 (Hospital
only)
Ceftazidime (as Ceftazidime pentahydrate) 2 gramFortum 2 g
powder for solution for injection vials| 1 vialP£ 17. 59 (Hospital
only)
Ceftazidime (as Ceftazidime pentahydrate) 3 gramFortum 3 g
powder for solution for injection vials| 1 vialP£ 25. 76 (Hospital
only)

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Ceftriaxone 15-Jun-2016


lINDICATIONS AND DOSE
Community-acquired pneumonia|Hospital-acquired
pneumonia|Intra-abdominal infections|Complicated
urinary-tract infections
▶BY INTRAVENOUS INFUSION
▶Neonate up to 15 days: 20 – 50 mg/kg once daily, doses at
the higher end of the recommended range used in
severe cases.

▶Neonate 15 days to 28 days: 50 – 80 mg/kg once daily,
doses at the higher end of the recommended range used
in severe cases.

▶Child 1 month–11 years (body-weight up to
50 kg): 50 – 80 mg/kg once daily, doses at the higher
end of the recommended range used in severe cases;
maximum 4 g per day
▶Child 9–11 years (body-weight 50 kg and above): 1 – 2 g
once daily, 2 g dose to be used for hospital-acquired
pneumonia and severe cases
▶Child 12–17 years: 1 – 2 g once daily, 2 g dose to be used
for hospital-acquired pneumonia and severe cases
▶BY INTRAVENOUS INJECTION
▶Child 9–11 years (body-weight 50 kg and above): 1 – 2 g
once daily, 2 g dose to be used for hospital-acquired
pneumonia and severe cases
▶Child 12–17 years: 1 – 2 g once daily, 2 g dose to be used
for hospital-acquired pneumonia and severe cases
▶BY DEEP INTRAMUSCULAR INJECTION
▶Child 1 month–11 years (body-weight up to
50 kg): 50 – 80 mg/kg daily, doses at the higher end of
the recommended range used in severe cases;
maximum 4 g per day
▶Child 9–11 years (body-weight 50 kg and above): 1 – 2 g
once daily, 2 g dose to be used for hospital-acquired
pneumonia and severe cases
▶Child 12–17 years: 1 – 2 g once daily, 2 g dose to be used
for hospital-acquired pneumonia and severe cases
Complicated skin and soft tissue infections|Infections of
bones and joints
▶BY INTRAVENOUS INFUSION
▶Neonate up to 15 days: 20 – 50 mg/kg once daily, doses at
the higher end of the recommended range used in
severe cases.

▶Neonate 15 days to 28 days: 50 – 100 mg/kg once daily,
doses at the higher end of the recommended range used
in severe cases.

▶Child 1 month–11 years (body-weight up to
50 kg): 50 – 100 mg/kg once daily, doses at the higher
end of the recommended range used in severe cases;
maximum 4 g per day

▶Child 9–11 years (body-weight 50 kg and above): 2 g once
daily
▶Child 12–17 years: 2 g once daily
▶BY INTRAVENOUS INJECTION
▶Child 9–11 years (body-weight 50 kg and above): 2 g once
daily
▶Child 12–17 years: 2 g once daily
▶BY DEEP INTRAMUSCULAR INJECTION
▶Child 1 month–11 years (body-weight up to
50 kg): 50 – 100 mg/kg daily, doses at the higher end of
the recommended range used in severe cases;
maximum 4 g per day
▶Child 9–11 years (body-weight 50 kg and above): 2 g once
daily
▶Child 12–17 years: 2 g once daily
Suspected bacterial infection in neutropenic patients
▶BY INTRAVENOUS INFUSION
▶Neonate up to 15 days: 20 – 50 mg/kg once daily, doses at
the higher end of the recommended range used in
severe cases.

▶Neonate 15 days to 28 days: 50 – 100 mg/kg once daily,
doses at the higher end of the recommended range used
in severe cases.

▶Child 1 month–11 years (body-weight up to
50 kg): 50 – 100 mg/kg once daily, doses at the higher
end of the recommended range used in severe cases;
maximum 4 g per day
▶Child 9–11 years (body-weight 50 kg and above): 2 – 4 g
once daily, doses at the higher end of the
recommended range used in severe cases
▶Child 12–17 years: 2 – 4 g once daily, doses at the higher
end of the recommended range used in severe cases
▶BY INTRAVENOUS INJECTION
▶Child 9–11 years (body-weight 50 kg and above): 2 – 4 g
once daily, doses at the higher end of the
recommended range used in severe cases; doses of
50 mg/kg or more should be given by infusion
▶Child 12–17 years: 2 – 4 g once daily, doses at the higher
end of the recommended range used in severe cases
▶BY DEEP INTRAMUSCULAR INJECTION
▶Child 1 month–11 years (body-weight up to
50 kg): 50 – 100 mg/kg daily, doses at the higher end of
the recommended range used in severe cases;
maximum 4 g per day
▶Child 9–11 years (body-weight 50 kg and above): 2 – 4 g
daily, doses at the higher end of the recommended
range used in severe cases
▶Child 12–17 years: 2 – 4 g daily, doses at the higher end of
the recommended range used in severe cases
Bacterial meningitis|Bacterial endocarditis
▶BY INTRAVENOUS INFUSION
▶Neonate up to 15 days: 50 mg/kg once daily.

▶Neonate 15 days to 28 days: 80 – 100 mg/kg once daily,
100 mg/kg once daily dose should be used for bacterial
endocarditis.

▶Child 1 month–11 years (body-weight up to
50 kg): 80 – 100 mg/kg once daily, 100 mg/kg once daily
dose should be used for bacterial endocarditis;
maximum 4 g per day
▶Child 9–11 years (body-weight 50 kg and above): 2 – 4 g
once daily, doses at the higher end of the
recommended range used in severe cases
▶Child 12–17 years: 2 – 4 g once daily, doses at the higher
end of the recommended range used in severe cases
▶BY INTRAVENOUS INJECTION
▶Child 9–11 years (body-weight 50 kg and above): 2 – 4 g
once daily, doses at the higher end of the

322 Bacterial infection BNFC 2018 – 2019


Infection

5

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