Nasal polyps
▶BY INTRANASAL ADMINISTRATION
▶Child 12–17 years: 64 micrograms twice daily for up to
3 months, dose to be administered into each nostrillUNLICENSED USERhinocort Aqua®is not licensed for use
in children.
lINTERACTIONS→Appendix 1 : corticosteroidslMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Spray
EXCIPIENTS:May contain Disodium edetate, polysorbates, potassium
sorbate
▶Budesonide (Non-proprietary)
Budesonide 64 microgram per 1 doseBudesonide
64 micrograms/dose nasal spray| 120 doseP£ 4. 77 DT = £ 4. 77
Budesonide 100 microgram per 1 doseBudeflam Aquanase
100 micrograms/dose nasal spray| 150 dosePs
Aircort 100 micrograms/dose nasal spray| 200 dosePs
▶Rhinocort(Johnson & Johnson Ltd)
Budesonide 64 microgram per 1 doseRhinocort Aqua 64 nasal
spray| 120 doseP£ 3. 77 DT = £ 4. 77
eiiiiF 698Fluticasone 21-Dec-2017
lINDICATIONS AND DOSE
Prophylaxis and treatment of allergic rhinitis and
perennial rhinitis
▶BY INTRANASAL ADMINISTRATION USING NASAL SPRAY
▶Child 4–11 years: 50 micrograms once daily, to be
administered into each nostril preferably in the
morning, increased if necessary to 50 micrograms twice
daily
▶Child 12–17 years: 100 micrograms once daily, to be
administered into each nostril preferably in the
morning, increased if necessary to 100 micrograms
twice daily; reduced to 50 micrograms once daily, dose
to be administered into each nostril, dose to be reduced
when control achieved
Nasal polyps
▶BY INTRANASAL ADMINISTRATION USING NASAL DROPS
▶Child 16–17 years: 200 micrograms 1 – 2 times a day, to
be administered into each nostril, alternative
treatment should be considered if no improvement
after 4 – 6 weeks, ( 200 micrograms is equivalent to
approximately 6 drops)
AVAMYS®SPRAY
Prophylaxis and treatment of allergic rhinitis
▶BY INTRANASAL ADMINISTRATION
▶Child 6–11 years: 27. 5 micrograms once daily, dose to be
sprayed into each nostril, then increased if necessary to
55 micrograms once daily, dose to be sprayed into each
nostril, reduced to 27. 5 micrograms once daily, to be
sprayed into each nostril, dose to be reduced once
control achieved; use minimum effective dose
▶Child 12–17 years: 55 micrograms once daily, dose to be
sprayed into each nostril, reduced to 27. 5 micrograms
once daily, to be sprayed into each nostril, dose to be
reduced once control achieved; use minimum effective
dose
DOSE EQUIVALENCE AND CONVERSION
▶ForAvamys®spray: 1 spray equivalent to
27. 5 micrograms.lINTERACTIONS→Appendix 1 : corticosteroids
lSIDE-EFFECTS
SIDE-EFFECTS, FURTHER INFORMATIONNasal ulceration
occurs commonly with nasal preparations containing
fluticasone furoate.lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Spray
EXCIPIENTS:May contain Benzalkonium chloride, disodium edetate,
polysorbates
▶Fluticasone (Non-proprietary)
Fluticasone propionate 50 microgram per 1 doseFluticasone
propionate 50 micrograms/dose nasal spray| 150 dosePsDT =
£ 11. 01
▶Avamys(GlaxoSmithKline UK Ltd)
Fluticasone furoate 27.5 microgram per 1 doseAvamys
27. 5 micrograms/dose nasal spray| 120 doseP£ 6. 44 DT = £ 6. 44
▶Flixonase(GlaxoSmithKline Consumer Healthcare, GlaxoSmithKline UK
Ltd)
Fluticasone propionate 50 microgram per 1 dosePirinase
Hayfever 0. 05 % nasal spray| 60 dosep£ 5. 05
Flixonase 50 micrograms/dose aqueous nasal spray| 150 doseP
£ 11. 01 DT = £ 11. 01
▶Nasofan(Teva UK Ltd)
Fluticasone propionate 50 microgram per 1 doseNasofan Allergy
50 micrograms/dose nasal spray| 60 dosep£ 4. 68
Nasofan 50 micrograms/dose aqueous nasal spray| 150 doseP
£ 8. 04 DT = £ 11. 01
▶Pirinase Hayfever(GlaxoSmithKline Consumer Healthcare)
Fluticasone propionate 50 microgram per 1 dosePirinase
Hayfever Relief for Adults 0. 05 % nasal spray| 60 doseG£ 5. 05
Nasal drops
EXCIPIENTS:May contain Polysorbates
▶Flixonase(GlaxoSmithKline UK Ltd)
Fluticasone propionate 400 microgramFlixonase Nasule
400 microgram/unit dose nasal drops| 28 unit doseP£ 12. 99 DT =
£ 12. 99Fluticasone with azelastine
The properties listed below are those particular to the
combination only. For the properties of the components
please consider,fluticasone above, azelastine hydrochloride
p. 698.lINDICATIONS AND DOSE
Moderate to severe seasonal and perennial allergic
rhinitis, if monotherapy with antihistamine or
corticosteroid is inadequate
▶BY INTRANASAL ADMINISTRATION
▶Child 12–17 years: 1 spray twice daily, dose to be
administered into each nostrillINTERACTIONS→Appendix 1 : antihistamines, non-
sedating.corticosteroidslMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Spray
EXCIPIENTS:May contain Benzalkonium chloride, polysorbates
▶Fluticasone with azelastine (Non-proprietary)
Fluticasone propionate 50 microgram per 1 actuation, Azelastine
hydrochloride 137 microgram per 1 actuationFluticasone
propionate 50 micrograms/dose / Azelastine 137 micrograms/dose
nasal spray| 120 dosePsDT = £ 14. 80
▶Dymista(Meda Pharmaceuticals Ltd)
Fluticasone propionate 50 microgram per 1 actuation, Azelastine
hydrochloride 137 microgram per 1 actuationDymista
137 micrograms/dose / 50 micrograms/dose nasal spray|
120 doseP£ 14. 80 DT = £ 14. 80eiiiiF 698Mometasone furoate 21-Dec-2017
lINDICATIONS AND DOSE
Prophylaxis and treatment of allergic rhinitis
▶BY INTRANASAL ADMINISTRATION
▶Child 6–11 years: 50 micrograms daily, dose to be
sprayed into each nostril700 Nasal inflammation, nasal polyps and rhinitis BNFC 2018 – 2019
Ear, nose and oropharynx12