eiiiiF 734
Clobetasone butyrate 21-Dec-2017
lINDICATIONS AND DOSE
Eczemas and dermatitis of all types|Maintenance
between courses of more potent corticosteroids
▶TO THE SKIN
▶Child:Apply 1 – 2 times a day, to be applied thinly
POTENCY
▶Clobetasone butyrate 0. 05 % cream and ointment:
moderate.
lUNLICENSED USELicensed for use in children (age range
not specified by manufacturer).
lPATIENT AND CARER ADVICEPatients or carers should be
advised on the application of clobetasone butyrate
containing preparations.
lEXCEPTIONS TO LEGAL CATEGORYCream can be sold to the
public for short-term symptomatic treatment and control
of patches of eczema and dermatitis (but not seborrhoeic
dermatitis) in adults and children over 12 years provided
pack does not contain more than 15 g.
lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug. Forms available from special-order
manufacturers include: cream, ointment
Ointment
CAUTIONARY AND ADVISORY LABELS 28
▶Clobavate(Teva UK Ltd)
Clobetasone butyrate 500 microgram per 1 gramClobavate
0. 05 % ointment| 30 gramP£ 1. 49 DT = £ 1. 86 | 100 gramP
£ 4. 35 DT = £ 5. 44
▶Eumovate(GlaxoSmithKline UK Ltd)
Clobetasone butyrate 500 microgram per 1 gramEumovate
0. 05 % ointment| 30 gramP£ 1. 86 DT = £ 1. 86 | 100 gramP
£ 5. 44 DT = £ 5. 44
Cream
CAUTIONARY AND ADVISORY LABELS 28
EXCIPIENTS:May contain Cetostearyl alcohol (including cetyl and
stearyl alcohol), chlorocresol
▶Eumovate(GlaxoSmithKline Consumer Healthcare, GlaxoSmithKline
UK Ltd)
Clobetasone butyrate 500 microgram per 1 gramEumovate
Eczema and Dermatitis 0. 05 % cream| 15 gramp£ 4. 11 DT = £ 4. 11
Eumovate 0. 05 % cream| 30 gramP£ 1. 86 DT = £ 1. 86 |
100 gramP£ 5. 44 DT = £ 5. 44
Combinations available:Clobetasone butyrate with nystatin
and oxytetracycline,p. 742
eiiiiF 734
Diflucortolone valerate 21-Dec-2017
lINDICATIONS AND DOSE
Severe inflammatory skin disorders such as eczemas
unresponsive to less potent corticosteroids (using 0. 3 %
diflucortolone valerate)|Short-term treatment of severe
exacerbations (using 0. 3 % diflucortolone valerate)|
Psoriasis (using 0. 3 % diflucortolone valerate)
▶TO THE SKIN
▶Child 1 month–3 years:Apply 1 – 2 times a day for up to
2 weeks, reducing strength as condition responds, to be
applied thinly
▶Child 4–17 years:Apply 1 – 2 times a day for up to
2 weeks, reducing strength as condition responds, to be
applied thinly; maximum 60 g per week
Severe inflammatory skin disorders such as eczemas
unresponsive to less potent corticosteroids (using 0. 1 %
diflucortolone valerate)|Psoriasis (using 0. 1 %
diflucortolone valerate)
▶TO THE SKIN
▶Child:Apply 1 – 2 times a day for up to 4 weeks, to be
applied thinly
POTENCY
▶Diflucortolone valerate 0. 1 % cream and ointment:
potent.
▶Diflucortolone valerate 0. 3 % cream and ointment: very
potent.
lUNLICENSED USENerisone®licensed for use in children
(age range not specified by manufacturer);Nerisone Forte®
not licensed for use in children under 4 years.
lSIDE-EFFECTSPustular psoriasis
lPRESCRIBING AND DISPENSING INFORMATIONPatients or
carers should be advised on application of diflucortolone
valerate containing preparations.
lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Ointment
CAUTIONARY AND ADVISORY LABELS 28
▶Nerisone(Meadow Laboratories Ltd)
Diflucortolone valerate 1 mg per 1 gramNerisone 0. 1 % ointment|
30 gramP£ 3. 98
Diflucortolone valerate 3 mg per 1 gramNerisone Forte 0. 3 %
ointment| 15 gramP£ 4. 70
Cream
CAUTIONARY AND ADVISORY LABELS 28
EXCIPIENTS:May contain Beeswax, cetostearyl alcohol (including cetyl
and stearyl alcohol), disodium edetate, hydroxybenzoates (parabens)
▶Nerisone(Meadow Laboratories Ltd)
Diflucortolone valerate 1 mg per 1 gramNerisone 0. 1 % cream|
30 gramP£ 3. 98
Nerisone 0. 1 % oily cream| 30 gramP£ 4. 95 DT = £ 4. 95
Diflucortolone valerate 3 mg per 1 gramNerisone Forte 0. 3 % oily
cream| 15 gramP£ 4. 70 DT = £ 4. 70
eiiiiF 734
Fludroxycortide 21-Dec-2017
(Flurandrenolone)
lINDICATIONS AND DOSE
Inflammatory skin disorders such as eczemas
▶TO THE SKIN
▶Child:Apply 1 – 2 times a day, to be applied thinly
POTENCY
▶Fludroxycortide 0. 0125 % cream and ointment: moderate
HAELAN®TAPE
Chronic localised recalcitrant dermatoses (but not acute
or weeping)
▶TO THE SKIN
▶Child:Cut tape tofit lesion, apply to clean, dry skin
shorn of hair, usually for 12 hours daily
lUNLICENSED USELicensed for use in children (age range
not specified by manufacturer).
lPATIENT AND CARER ADVICEPatients or carers should be
counselled on application offludroxycortide cream and
ointment.
lMEDICINAL FORMS
There can be variation in the licensing of different medicines
containing the same drug.
Ointment
CAUTIONARY AND ADVISORY LABELS 28
EXCIPIENTS:May contain Beeswax, cetostearyl alcohol (including cetyl
and stearyl alcohol), polysorbates
▶Fludroxycortide (Non-proprietary)
Fludroxycortide 125 microgram per 1 gramFludroxycortide
0. 0125 % ointment| 60 gramP£ 5. 99
Cream
CAUTIONARY AND ADVISORY LABELS 28
EXCIPIENTS:May contain Cetostearyl alcohol (including cetyl and
stearyl alcohol), propylene glycol
BNFC 2018 – 2019 Eczema and psoriasis 737
Skin
13