USMLE Step 2 CK Lecture Notes 2019: Obstetrics/Gynecology (Kaplan Test Prep)

AMNIOCENTESIS

Amniocentesis is a diagnostic, outpatient office procedure performed after 15
weeks under U/S guidance without anesthesia. Pregnancy loss rate is 0.5%

Figure I-3-6. Amniocentesis

A   needle  is  placed  into    a   pocket  of  amniotic    fluid   under   direct  U/S guidance,

aspirating  amniotic    fluid   containing  desquamated living  fetal   cells

(amniocytes).

Fetal   karyotyping is  performed   on  amniocytes. NTD (neural tube    defect)

screening   is  performed   on  amniotic    fluid   with    biochemical analysis    (AFP    and

acetylcholinesterase).

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