OB TRIAD
Human Placental Lactogen (hPL)Its effect is to antagonize the cellular action of insulin, decreasing insulin
utilization and thereby contributing to the predisposition of pregnancy to glucose
intolerance and diabetes.
If levels are low, threatened abortion or intrauterine growth restriction
(IUGR) can occur.
Produced by syncytiotrophoblast
Similar to HGH, prolactin
Decreases insulin sensitivity