USMLE Step 2 CK Lecture Notes 2019: Obstetrics/Gynecology (Kaplan Test Prep)

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There is no adverse effect on maternal outcome, but preterm births and stillbirths
are increased.


Management. Oral antihistamines for mild cases. Cholestyramine has been used
to decrease enterohepatic circulation.


Ursodeoxycholic acid    is  the treatment   of  choice. Antenatal   fetal   testing
should be initiated at 34 weeks. Symptoms disappear after delivery.
Induce labor at 37 weeks gestation.
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