to have no negative effects on pregnancy with regard to preterm labor or
malpresentation.
DES Uterus
The daughters of mothers exposed to diethylstilbestrol (DES) during pregnancy
are predisposed to uterine abnormalities and clear cell carcinoma of the vagina.
The mechanism by which DES disrupts normal uterine development is not
known.
>70% have abnormalities, including a small, incompletely formed uterus
(“hypoplastic”) and/or a T-shaped cavity.
50% have cervical defects (e.g., an incompletely formed cervix that
predisposes to cervical insufficiency).