CHANCROID
Chancroid is caused by Haemophilus ducreyi, a gram-negative bacterium. It is
uncommon in the United States. It is a cofactor for HIV transmission.
Chancroid is one of two STDs which present with a painful ulcer. A pustule,
usually on the vulva, becomes a painful ulcer within 72 hours, with a typically
“ragged edge.”
Diagnosis. A positive culture confirms the diagnosis, although a diagnosis is
often made clinically after excluding syphilis and genital herpes.
Management. Single oral dose of azithromycin, single IM dose of ceftriaxone,
or oral erythromycin base for seven days (CDC-recommended treatment).
Figure II-7-1. Pathophysiology of Chancroids