Patients with idiopathic precocious puberty should be maintained with inhibition
of the hypothalamic–pituitary–ovarian axis until the chronologic age catches up
with the bone age.
Table II-12-2. Management of Precocious Puberty
Idiopathic GnRH agonist
CNS lesions Medical or surgical treatment
Ovarian tumor Surgical excision
McCune-Albright Aromatase inhibitors
enzyme inhibitor.
Granulosa cell tumor (rare) is a gonadal-stromal cell ovarian tumor that
autonomously produces estrogen. A pelvic mass will be identified on
examination or pelvic imaging. Management: Surgical removal of the
tumor.