USMLE Step 2 CK Lecture Notes 2019: Obstetrics/Gynecology (Kaplan Test Prep)

(Kiana) #1

NORMAL BREAST DEVELOPMENT


EMBRYOLOGY


Breasts begin developing in the embryo about 7–8 weeks after conception,
consisting only of a thickening or ridge of tissue.


From    weeks   12–16,  tiny    groupings   of  cells   begin   to  branch  out,    laying  the
foundation for future ducts and milk-producing glands. Other tissues develop
into muscle cells that will form the nipple (the protruding point of the breast)
and areola (the darkened tissue surrounding the nipple).
In the later stages of pregnancy, maternal hormones cause fetal breast cells to
organize into branching, tube-like structures, thus forming the milk ducts. In
the final 8 weeks, lobules (milk-producing glands) mature and actually begin
to secrete a liquid substance called colostrum.
In both female and male newborns, swellings underneath the nipples and
areolae can easily be felt, and a clear liquid discharge (colostrum) can be seen.
Free download pdf