Handbook of Herbs and Spices - Volume 3

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Herbs, spices and cardiovascular disease 135


in their food to achieve the same objective. Consumption of the complex composition


of the crude herb or spice would seem to have a distinct advantage over the use of


single compound supplements.


8.6 Conclusions.....................................................................................


Herbs and spices have been used as sources of flavourings and medicines for thousands


of years and their use as flavourings continues today. Now the pharmaceutical industry


is interested in these plants as a source of pharmaceuticals, particularly for their


antioxidant value in the prevention and treatment of chronic diseases such as


cardiovascular disease. One aim has been to isolate and identify single compounds


from individual herbs or spice plants so that the compound can then be marketed as


being of ‘natural’origin. However, examination of the effect of single plant based


compounds have not been as encouraging as the use of crude extracts. The difference


rests on the fact that the plant contains a very large number of potential anti-oxidants


that probably act synergistically. This is not surprising. In order to control the possibility


of excess solar energy damaging cell metabolism, evolution has ensured that plants


contain not one compound but a whole variety of compounds to achieve an anti-


oxidant effect. It is not surprising therefore that animals including ourselves who


depend on plants for food have co-evolved and have therefore the same requirement


for multiple anti-oxidants rather than a single one. The conclusion that can be drawn


from such an evolutionary view is that however commercially attractive and convenient


it might be to take a single compound supplement, it is more sensible and beneficial


to take a complex extract. It is far better to use the herbs and spices for their original


purpose, which is to enhance the flavour of our food and at the same time ensure that


we remain healthy on a balance of antioxidants.


8.7 References.......................................................................................


AHMED RS, SETH V, PASHA ST and BANERJEE BD (2000) Influence of dietary ginger (Zingiber officinales
Rosc.) on oxidative stress induced by malathion in rats. Food and Chemical Toxicology 38,
443–50.
BELLAMY D (2003) The Bellamy Herbal. A Whole World Herbal Handbook for 21st Century Families.
Century, London.
BENZIE IF (2003) Evolution of dietary antioxidants. Comparitive Biochemistry and Physiology. A.
Molecular and Integrative Physiology 136, 113–26.
BENZIE IF and STRAIN JJ (1996) The ferric reducing ability of plasma (FRAP) as a measure of
‘antioxidant power’: the FRAP assay. Analytical Biochemistry 239, 70–76.
BHATTACHARYYA G and LIBBY P (1998) Atherosclerosis In Pathophysiology of Heart Disease. LS Lilly,
ed., Williams and Wilkins, London, New York, p 101–118.
BLOCK, E (1996) The health benefits of organosulfur and organoselenium compounds in garlic
(Allium sativum): recent findings. In Hypernutritious Foods, eds JW Finley, DJ Armstrong, S
Nagy and SF Robinson, ACS Symposium, Auburral, Florida, USA, 261–292.
BLOMHOFF R (2005) Dietary antioxidants and cardiovascular disease. Current Opinion in Lipidology
16, 47–54.
BORDIA A, VERMA SK and SRIVASTAVA KC (1997) Effect of ginger (Zingiber officinale Rosc.) and
fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation
in patients with coronary artery disease. Prostaglandins, Leukotrienes and Essential Fatty Acids
56, 379–84.

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