B
Gonorrhea (f; DEP); Gravel (f; CRC); Headache (1; CRC; PHR); Head Cold (1; RIN); Hemorrhoid
(f; DEP; HHB; PH2; SKJ); Hepatosis (f; JLH); Hiccup (f; PH2); High Blood Pressure (1; CRC); High
Cholesterol (1; LIN; SPI); Induration (f; JLH); Infection (1; CRC; JBU; MPI; WOI); Itch (f; DEP);
Leishmaniasis (1; PHR); Lethargy (1; DAD); Low Blood Pressure (1; SPI); Malaria (f; CRC; DEP);
Mucososis (f; PH2; RIN); Mycosis (1; CRC; HG50; MPI; WOI); Nausea (f; CRC); Neuralgia (1; HHB;
PHR; PH2); Ophthalmia (f; JLH); Pain (1; JBU); Paralysis (f; CRC; DEP); Paraplegia (1; CRC; DAD;
DEP; WOI); Parturition (f; CRC); Phymata (f; JLH); Prolapse (f; DEP); Respirosis (f; SPI); Rhinosis
(f; SKJ); Ringworm (1; HG50); Scabies (1; PHR; PH2); Scarlatina (1; CRC; DAD); Scirrhus (f; JLH);
Snakebite (f; SKJ); Sore Throat (f; DEP; SKJ); Splenosis (f; JLH); Staphylococcus (1; MPI); Stom-
achache (f; DAA); Swelling (f; JLH); Tapeworm (1; MPI); Tinea (1; HG50); Toothache (1; DEP; FNF);
Tumor (1; CRC); Ulcer (f; JLH); Urethrosis (f; PH2); Urolithiasis (1; CRC); Vertigo (f; CRC); Vomiting
(f; PH2); Wart (f; JLH); Water Retention (f; PNC; SKJ); Wen (f; JLH); Yeast (1; HG50).
Dosages (Black Pepper) — Single doses 300–600 mg; daily dosage 1500 mg (HHB; PHR); 5–15
whole peppercorns for hemorrhoids (HHB); 1–15 grains (MAD); spice chicken soup with black
pepper for congestion, cough, or head cold (RIN).
Contraindications, Interactions, and Side Effects (Black Pepper) — Class 1 (AHP) “Hazards
and/or side effects not known for proper therapeutic dosages” (PH2).
Extracts (Black Pepper) — In human volunteers, 20 mg piperine increases bioavailability of
curcumin 20-fold (MAB). Piperine inhibits calcium transport into the mitochondria, facilitates
mitochondrial release of calcium, and stimulates ATPase activity (SPI). Piperine is more potent
than D-galactosamine in inhibiting glucuronidation. (ED50 with 3-hydroxybenzo(a)pyrene = 50
μM) (SPI). Piperine both depletes uridine diphosphate glucuronic acid and reduced the rate of
glucuronidation. This could lead to drug potentiation. Piperine is more toxic to houseflies than
pyrethrin. A mix of 0.05% piperine and 0.01 pyrethrins is more toxic than 0.1% pyrethrin (WOI).
According to Rinzler, chavicine, piperidine, and piperine are all diaphoretic (but none of them were
in my database at home as such) (RIN). Ayurvedics often prescribe black pepper in a synergistic
triad called trikatu, with ginger and long pepper (DEP). In addition to 0.54% mixed tocopherols
in the oleoresin (including 0.1% alpha-tocopherol), pepper contains five phenolic amides that are
superior as antioxidants to alpha tocopherol in vitro (SPI). Although pepper contains the carcinogen
safrole, it is at very low levels compared to sassafras. EO reportedly inhibits Alternaria oryzae, A.
tenuis, Aspergillus oryzae, Beauveria sp., Cryptococcus neoformans, Fusarium solani, Histoplasma
capsulatum, Microsporum gypseum, Nocardia brasiliensis, Penicillium javanicum, P. striatum,
Staphylococcus “albus,” Trichoderma viride, Trichophyton mentagrophytes, and Vibrio cholera.
Alcoholic, aqueous, and ether extracts have taenicidal activity at 1:100 concentrations. Aqueous
leaf extract raised blood pressure in dogs modestly (not stated whether oral or injected).
BLACK PHYSICNUT (Jatropha gossypiifolia L.) XActivities (Black Physicnut) — Allergenic (f; CRC); Antibacterial (1; CRC); Antidote, hippomane (f;
CRC); Antiplasmodial (1; MPG); Antiseptic (1; CRC); Antispasmodic (1; MPG); Antiviral (1; MPG);
Cicatrizant (f; DAV); CNS-Depressant (1; MPG); Depurative (f; CRC); Ecbolic (f; CRC); Emetic (1;
CRC); Hypoglycemic (1; MPG); Laxative (1; CRC); Molluscicide (f; MPG); Piscicide (1; CRC); Poison
(1; CRC); Sedative (1; ZUL); Uterotonic (f; MPG); Vermifuge (f; MPG); Vulnerary (f; MPG).
Indications (Black Physicnut) — Anorexia (f; MPG); Arthrosis (f; MPG); Asthma (f; CRC); Bacteria
(1; CRC); Bleeding (f; IED); Burn (f; CRC; DAV); Cancer (1; CRC; JLH); Cancer, lung (1; MPG);
Carbuncle (f; CRC); Carcinoma (1; CRC); Catarrh (f; MPG); Cholecystosis (f; MPG); Cold (f; CRC);
Constipation (1; CRC; IED); Convulsion (1; MPG); Cramp (1; MPG); Dermatosis (f; CRC); Diabetes
(f; CRC; IED; MPG); Diarrhea (f; CRC; IED); Dropsy (f; CRC); Dyspepsia (f; CRC; IED); Eczema
(f; CRC); Erysipelas (f; DAV); Escherichia (1; CRC); Flu (f; DAV); Gall (f; CRC); Glossosis (f;