C
CRC; FNF; JLH); Cancer, stomach (1; CRC; FNF; JLH; PH2); Cancer, testicle (1; CRC; FNF;
JLH); Cancer, tongue (1; CRC; FNF; JLH); Cancer, urethra (1; CRC; FNF; JLH); Cancer,
uterus (1; CRC; FNF; JLH); Candida (1; HH2; MAB); Catarrh (f; HHB; PHR); Cholangosis
(2; MAB); Cholecystosis (2; CRC; HHB; MAB; MAD; PHR; PH2); Cholelithiasis (2; MAB);
Colitis (1; MAB); Colonic Polyposis (2; MAB); Condylomata (1; CRC; HH2; MAB); Corneal
Opacity (f; MAB; MAD); Corn (f; CRC; PNC); Cramp (2; HHB; KOM; MAB; PH2; SHT);
Dermatosis (f; PH2); Dysmenorrhea (1; PHR); Dyspepsia (f; MAB); Eczema (f; CRC; FAD);
Edema (f; MAD; PHR; PH2); Egilops (f; CRC); Enterosis (2; HHB; KOM; MAB); Epithelioma
(f; MAD); Escherichia (1; HH2); Exanthema (f; MAD); Fever (f; CRC; MAD); Fistula (f;
MAD); Freckle (f; CRC; MAD); Frigidity (f; CRC); Fungus (1; HH2; MAB); Gallstone (f;
MAD); Gastrosis (2; BRU; HHB; KOM; MAB); Gastrospasm (2; KOM); Gonorrhea (f; MAD);
Gout (f; CRC; MAD; PHR; PH2); Headache (f; MAB); Hematuria (f; MAD); Hemorrhoid (1;
CRC; FAD); Hepatosis (2; CRC; MAB; MAD; PHR; PH2); Herpes (1; MAB); High Blood
Pressure (1; KOM; PHR; PH2; PNC); Hyperglycemia (f; CRC); Hypertonia (f; KOM; PH2);
Hypochondria (f; MAD); IBS (2; MAB); Immunodepression (1; KOM; PH2); Induration (f;
CRC); Infection (1; HH2; MAB); Inflammation (1; FAD; MAB; PNC); Insomnia (f; CRC;
HHB); Jaundice (f; CRC; HHB; MAB; MAD; PHR; PH2); Lupus (f; MAD); Malaria (f; MAD);
Mastosis (f; JLH; PH2); Migraine (1; MAB); Myalgia (f; HHB); Mycosis (1; HH2; MAB);
Nervousness (f; CRC; HHB); Neuralgia (f; HHB); Ophthalmia (f; MAD); Pain (1; CRC; HHB;
PH2; PNC); Parotosis (f; JLH); Pertussis (2; MAB; MAD; PNC); Pharyngosis (f; PH2);
Phimosis (f; MAD); Phthisis (f; MAD); Pneumonia (f; HHB; MAD); Polyp (2; CRC; MAB;
PHR; PH2); Psoriasis (1; CRC; MAB; MAD); Rash (f; PH2); Respirosis (f; MAD); Rheuma-
tism (f; HHB); Rhinosis (f; JLH; PH2); Ringworm (f; CRC; FAD); Scabies (f; MAD; PHR;
PH2); Scurvy (f; CRC); Scrofula (f; CRC); Sore (f; MAD); Shigella (1; HH2); Splenosis (f;
MAD); Staphylococcus (1; HH2; MAD); Stomachache (f; HHB); Stone (f; HHB; MAD; PHR);
Tenesmus (f; MAD); Toothache (f; MAD; PHR); Tuberculosis (f; MAD); Tumor (1; CRC;
MAB); Ulcer (f; CRC); Vaginosis (1; MAB); Vertigo (f; MAD); Virus (1; BRU; MAB); Wart
(f; CRC; HHB; MAB; MAD; PHR); Water retention (1; MAD; PNC); Wen (f; CRC); Wound
(f; CRC; FAD); Yeast (1; HH2; MAB). “Spastic discomfort of the bile ducts and gastrointestinal
tract” (KOM).
Dosages (Celandine) — 0.5 g herb single dose (HHB); 3–9 g herb/day (MAB); 2–5 g crude
herb (or 12–30 mg total alkaloids) (KOM; SHT); 0.5 g root (PHR); 2–4 ml liquid extract
(PNC); 1–2 ml/day fluid extract (1:2) (MAB); 2–4 ml/day tincture (1:5) (MAB); 1.8–7.5 g
juice (MAD).
Contraindications, Interactions, and Side Effects (Celandine) — Class 2b, 2d (AHP). None
known (KOM). Not to be used by children (AHP). Canadian regulations do not allow celandine
in food. Australians counsel that it “may affect glaucoma treatment.” Germans report that it
takes more than 500 g celandine to cause toxic effects in cattle and horses (AHP). Side effects
include dry mouth and dizziness (PNC). Overdoses can cause dizziness, hematuria, intestinal
colic, stomach pain, and urinary urgency (SHT). Consumption of fresh herb may cause GI
distress (AHP). Stem juice allergenic, irritant, and paralytic (FAD). “Thought to be hepato-
toxic” (BRU).
Extracts (Celandine) — Extracts, as well as chelidonine, chelerythrine, protopine, and sangui-
narine have antibacterial and antitussive activities (PNC). Chelidonine lowers arterial blood pres-
sure, relaxes smooth muscle spasms and bronchial spasm, increases urine production, and delays
or inhibits the development of anaphylactic shock in vivo. Alpha-allocryptopine, chelidonine, and
sanguinarine have in vivo analgesic activities (PNC). LD50 (decoction) 9500 mg/kg ipr mouse
(MAB); LD50 (alkaloids) 300 mg/kg scu mouse (MAB).