C
Tumor (1; HH2; PHR; PNC); Ulcer (f; HHB); VD (f; CRC); Vomiting (f; PH2); Water Retention
(f; CRC).
Dosages (Condor Plant) — 1–4 g powdered bark (PNC); 1.5 g bark/cup tea (HHB); average daily
dose bark 2–4 g (HH2; PHR); 2–4 g/day (HH2); 0.2–0.5 g aqueous extract (?); 0.5–4 ml tincture
(HHB); 2–5 g tincture; 2–4 g liquid extract (PHR); 2–4 ml liquid extract (PNC); 1 cup wine 30
minutes before meals (50–100 g/liter wine) (PH2).
Contraindications, Interactions, and Side Effects (Condor Plant) — Not covered (AHP). “Haz-
ards and/or side effects not recorded for proper therapeutic dosages” (PH2). No side effects reported
during therapeutic use (AEH; PHR).
CONESSI, KURCHI (Holarrhena pubescens Wall. ex G. Don) +Synonyms — Chonemorpha antidysenterica (Roxb. ex Fleming) G. Don, Echites antidysenterica
Roth, Holarrhena antidysenterica (Roxb. ex Fleming) Wall. ex A. DC., H. febrifuga Klotzsch.
Activities (Conessi) — Amebicide (1; WOI); Anesthetic (1; WOI); Anthelminthic (1; KAP; WOI);
Antidysenteric (1; WOI); Antiinflammatory (f; KAB); Antipyretic (1; KAP; SUW; WOI); Antis-
pasmodic (1; MPI); Antitubercular (f; WOI); Antiviral (f; MPI); Aperitif (f; KAB; SKJ); Aphrodisiac
(f; KAB); Astringent (1; KAP; MPI; SUW; WOI); Cardiodepressant (1; MPI); Carminative (f;
KAB; KAP; MPI); Diuretic (f; WOI); Hypoglycemic (1; MPI); Hypotensive (1; KAP; MPI);
Lactagogue (f; KAB); Narcotic (f; WOI); Protisticide (1; WOI); Stomachic (1; KAP; MPI; WOI);
Tonic (1; WOI); Vasodilator (1; MPI); Vulnerary (f; KAB).
Indications (Conessi) — Ameba (1; WOI); Amebiasis (1; MPI; WOI); Anorexia (f; KAB; SKJ);
Asthma (f; KAB); Bite (f; MPI); Bleeding (1; WOI); Boil (f; MPI; WOI); Bronchosis (f; WOI);
Cancer (1; MPI); Cholera (f; MPI); Colic (f; WOI); Constipation (f; MPI; SKJ); Cramp (1; MPI);
Dermatosis (f; WOI); Diabetes (1; MPI); Diarrhea (1; SUW; WOI); Dropsy (f; SUW; WOI);
Dysentery (1; KAP; MPI; SUW; WOI); Dysmenorrhea (f; KAB); Dyspepsia (f; WOI); Dysuria
(f; SKJ); Epilepsy (f; SKJ); Epistaxis (1; WOI); Erysipelas (f; KAB); Fatigue (f; KAB); Fever
(1; KAB; KAP; SUW; WOI); Gas (f; KAB; KAP; MPI); Gingivosis (f; KAB); Headache (f;
KAB); Hematuria (f; MPI; SKJ); Hemorrhoid (f; KAB; WOI); High Blood Pressure (2; KAP;
MPI); Hyperglycemia (1; MPI); Infertility (f; WOI); Inflammation (f; KAB); Jaundice (f; MPI);
Leprosy (f; SKJ); Leukoderma (f; KAB; SKJ); Lumbago (f; KAB); Malaria (f; KAP); Menor-
rhagia (f; MPI); Myalgia (f; KAB); Pain (1; WOI); Parturition (f; KAB); Pulmonosis (f; WOI);
Rhinosis (f; MPI); Snakebite (f; SKJ); Sore (f; WOI); Splenosis (f; SKJ; WOI); Spermatorrhea
(f; MPI); Stomachache (f; MPI); Trichomoniasis (f; WOI); Toothache (f; WOI); Trypanosoma
(1; MPI); Tuberculosis (1; WOI); Urethrosis (1; IWU); Virus (1; MPI); Water Retention (f; WOI);
Worm (1; SKJ; SUW; WOI).
Dosages (Conessi) — 2–4 g powdered seed (KAP); 28–74 ml decoction or tea (KAP); 2–4 ml
tincture (KAP); daily dose of 60–120 grains powdered bark in 3–4 portions (KAB); bark taken in
decoction (WOI); doses >500 mg/person may be toxic.
Contraindications, Interactions, and Side Effects (Conessi) — Not covered (KOM; PHR; AHP;
APA). Doses of conessine >500 mg day may induce GI distress, insomnia, restlessness, tremors,
vertigo, possibly even death from central respiratory paralysis (WBB; WOI). LD50 (50% ethanolic
fruit extract) = 250 mg/kg ipr mouse (MPI). LD50 (50% ethanolic sb extract) = 1000 mg/kg ipr
mouse (MPI). With at least 18 alkaloids, is the conessine most important at 4000 ppm. Conessine
increases coronary outflow in isolated animal tissues. Induces narcosis in frogs and is locally
anesthetic in guinea pigs, being “twice as active as cocaine.” Subcutaneous injections may induce
necrosis. Conessine has antiamebic activities comparable to emetine.