C
Contraindications, Interactions, and Side Effects (Cranesbill) — Class 1 (AHP). “Health haz-
ards not known with proper therapeutic dosages” (PH2).
CREAT (Andrographis paniculata (Burm. f.) Wall. ex Nees.) +Synonym — Justicia paniculata Burm. f.
Activities (Creat) — Abortifacient (1; KEB); Adaptogen (f; KEB); Adrenocortical Stimulant (1;
KEB); Alterative (f; SKJ); Analgesic (1; MAB; WO2); Anthelmintic (1; MAB); Antiaggregant
(2; KEB); Antiandrogenic (1; KEB); Antiatherosclerotic (1; MAB); Antibacterial (1; KEB); Anti-
HIV (1; MAB); Antifertility (1; KEB); Antiinflammatory (2; KEB; MAB); Antiischemic (1;
KEB; MAB); Antileukemic (1; MAB); Antioxidant (1; MAB); Antipyretic (2; KEB; MAB);
Antiradicular (1; MAB); Antiseptic (f; WO2); Antiserotonin (2; KEB); Antispermatogenic (1;
KEB); Antityphoid (1; WO2); Antiulcer (1; MAB); Bitter (2; KEB); Cholagogue (f; WO2);
Choleretic (1; KEB); Contraceptive (1; KEB); Depurative (f; WO2); Fibrinolytic (1; KEB);
Fungicide (1; WO2); Hepatoprotective (1; KEB; MAB); Hypoglycemic (1; KEB; MAB);
Hypotensive (1; MAB); Immunostimulant (1; KEB; MAB); Phagocytotic (1; MAB); Stomachic
(f; SKJ); Tonic (f; SKJ).
Indications (Creat) — Anorexia (F; MAB); Atherosclerosis (1; KEB; MAB); Bacteria (1;
KEB; WO2); Bronchosis (f; WO2); Cachexia (f; SKJ); Cardiopathy (f; KEB); Cholera (f;
WO2); Cold (1; MAB); Debility (f; WO2); Dermatosis (F; MAB); Diabetes (f; MAB; WO2);
Diarrhea (1; MAB); Dog Bite (f; SKJ); Dysentery (2; KEB; MAB); Dyspepsia (f; MAB; SKJ);
Enterosis (2; KEB; MAB); Escherichia (1; WO2); Fever (2; KEB; MAB); Flu (f; WO2); Fungus
(1; WO2); Gonorrhea (f; WO2); Hemorrhoid (f; WO2); Hepatosis (2; KEB; MAB); High Blood
Pressure (1; MAB); HIV (1; MAB); Hyperglycemia (1; KEB; MAB); Immunodepression (1;
KEB; MAB); Infection (1; KEB; WO2); Inflammation (2; KEB; MAB); Ischemia (1; MAB);
Itch (f; SKJ); Jaundice (f; WO2); Leprosy (2; KEB); Leptospirosis (2; KEB); Leukemia (1;
MAB); Malaria (1; KEB); Mycosis (1; WO2); Nephrosis (2; KEB); Pain (1; MAB; WO2);
Pharyngosis (2; KEB; MAB); Pyelonephrosis (2; KEB); Respirosis (2; KEB; MAB); Restenosis
(1; KEB); Salmonella (1; WO2); Sinusosis (2; MAB); Snakebite (2; KEB; MAB); Sore (f;
SKJ); Sore Throat (2; KEB); Splenosis (f; SKJ); Stenosis (1; KEB; MAB); Swelling (f; WO2);
Syphilis (f; SKJ); Tonsilosis (2; KEB; MAB); Tuberculosis (2; KEB); Ulcer (1; MAB); UTI
(2; MAB); Vitiligo (f; WO2); Worm (1; KEB).
Dosages (Creat) — 1.5–6 g dry herb/day or 3–12 ml fluid extract (1:2) (KEB).
Contraindications, Interactions, and Side Effects (Creat) — Class 2b (abortifacient); large oral
doses may cause GI distress, anorexia, and emesis (AHP; KEB). Contraindicated in pregnancy
(KEB). Urticaria is a rare side effect (4%) (MAB). Andrographolides LD50 = 13,400–40,000 mg/kg
orl (MAB).
CUBEB (Piper cubeba L. f.) ++Activities (Cubeb) — Antibacterial (1; MPI); Antiseptic (1; MPI; PH2); Antiviral (1; PNC);
Aphrodisiac (f; DEP; MAD; PH2); Astringent (1; PH2); Carminative (f; DEP; MAD); Diuretic (f;
DEP; PNC); Expectorant (1; DEP; PH2; PNC); Fungicide (1; MPI); Laxative (f; MAD); Litholytic
(f; MAD); Memorigenic (f; PH2); Sedative (f; WOI); Stimulant (f; DEP); Tonic (f; IHB); Urinary
Antiseptic (1; WOI); Vibriocide (1; MPI).