A
CAN); Tuberculosis (1; BGB); Tumor (f; CRC); Ulcer (f; CRC; HHB); UTI (2; PH2); Water
Retention (f; BGB; CAN; CRC; PHR; PH2).
Dosages (Angelica) — 1 tsp powdered leaf, root, or seed/cup of water (APA); 1.5 g root (1 tsp =
~1.5 g)/day (BIS); 4.5 g root (BIS; KOM; PH2); 1–2 g root in tea 3 ×/day (CAN); 0.5–2 g powdered
root (PNC); 1–2 g seed day (CAN); 2–5 g dry leaf 3 ×/day (CAN); 2–5 ml leaf tincture (1:5 in
45% alcohol) 3 ×/day (CAN); 0.5–2 ml root tincture (1:5 in 50% alcohol) 3 ×/day (CAN); 1.5 g
root tincture (1:5) (KOM); 2–5 ml leaf extract (1:1 in 25% alcohol) 3 ×/day (CAN); 0.2–5 ml root
extract (1:1 in 25% alcohol) 3 ×/day (CAN); 2–4 ml liquid root extract (PNC); 2–4 ml liquid herb
extract (PNC); wineglass of root tea (PNC).
Contraindications, Interactions, and Side Effects (Angelica) — Class 2b, 2d (avoid prolonged
exposure to sunlight) (AHP). Contraindicated for peptic ulcer. Commission E reports photosensi-
tivity due to furocoumarins (AEH). Furanocoumarins may cause phototoxic dermatosis (CAN).
Anticoagulant coumarins may interact with anticoagulant therapy, additively or synergistically, or
perhaps even antagonistically. Angelica and root oils reported to cause photodermatosis and pho-
totoxicity, respectively. Root oil should be limited to 7800 ppm in skin products when the skin is
to be exposed to UV. Root Oil LD50 = 2200 mg/kg orl mouse; LD50 = 1160 mg/kg orl rat (CAN);
toxic in rats 1870 mg/kg (BIS); LD50 = >5000 mg/kg top. rabbit (CAN). We may extend to all
apiaceous oils Bisset’s comments on celeryseed oil, “The drug is contraindicated in inflammation
of the kidneys,” since apiaceous EOs may increase the inflammation as a result of epithelial irritation
(BIS). Bergapten is a suspected carcinogen. Angelica root, reportedly abortifacient, should not be
used in “pregnancy and lactation in amounts exceeding those used in foods” (CAN). Canadians
list “as an unacceptable non-medicinal ingredient for oral use products” (AHP). Do not use if fever,
chills, headache, thirst, sweating, and a rapid pulse are present (TMA, 1996). Is this any worse
than celery, parsnip, and other furanocoumarin-containing herbs in the carrot family, even carrot
itself? Until I answer this question without bias, I don’t know that it deserves the low score given
it by AHA. It does contain at least 15 different coumarin-like compounds, probably shared with
many other umbelliferae (Apiaceae).
ANGLED LOOFAH, CHINESE OKRA
(Luffa acutangula (L.) Roxb.) ++Synonym — Cucumis acutangulus L.
Activities (Angled Loofah) — Abortifacient (1; KAP; MPI); Antipyretic (f; KAB); Bitter (f; DEP);
Demulcent (f; KAP; WOI); Diuretic (f; KAP; WOI); Emetic (f; DEP; WOI); Expectorant (f; WOI);
Hypoglycemic (1; KAP); Laxative (f; DEP; KAP; WOI); Tonic (f; DEP); Vermifuge (f; KAB).
Indications (Angled Loofah) — Amenorrhea (f; WOI); Asthma (f; KAB; WOI); Biliousness (f; KAB);
Bite (f; KAP); Bronchosis (f; KAB); Conjunctivosis (f; DEP; WOI); Dermatosis (f; KAP; WOI); Diabetes
(1; KAP); Dropsy (f; KAP); Dysentery (f; DEP; KAP); Fever (f; KAB); Gonorrhea (f; DEP); Hemorrhoid
(f; DEP; KAB; KAP; WOI); Hyperglycemia (1; KAP); Jaundice (f; DEP; WOI); Leprosy (f; DEP; KAB;
KAP; WOI); Ringworm (f; KAB; KAP); Snakebite (f; KAP); Sore (f; KAP; WOI); Splenosis (f; DEP;
KAB; WOI); Uremia (f; WOI); VD (f; DEP); Water Retention (f; KAP; WOI); Worm (f; KAB).
Dosages (Angled Loofah) — 1.5–2 g to 10 seed as demulcent (KAP); 5–10 g fruit juice (KAP);
28–56 ml infusion (KAP). LD50 (50% Ethanolic Extract) = 1000 mg/kg ipr mouse (MPI).
ANGOSTURA (Angostura trifoliata (Willd.) T. S. Elias) ++Synonyms — Bonplandia trifoliata Willd., Galipea officinalis Hancock; Cusparia febrifuga Humb.
ex DC., Cusparia trifoliata (Willd.) Engl.