where   you were    the moment  you heard   of  the 9/11    attacks
on  the World   Trade   Center? I’ll    bet that    day is  burned  into
your    memory  in  crystal-clear,  stunning    detail. This    is  owed
to  none    other   than    norepinephrine.
The main    hub of  norepinephrine  is  a   small   region  in  the
brain    known   as  the    locus   coeruleus.  Any  stressful   stimuli
lead    to  an  increase    in  norepinephrine, from    a   terrorist   attack
to  a   major   fight   with    a   significant other   to  simply  not eating
for  twenty-plus     hours.  Evolutionarily  speaking,   this    is  an
important    adaptive    function.   For     much    of  our     time    on  the
planet,  stressful   stimuli     required    our     immediate   attention,
and detailed,   long-lasting    memories    needed  to  be  formed  to
avoid    such    an  event   in  the     future  (provided   that    we  lived
through  that    initial     encounter).     This    is  called long-term
potentiation,    and     it  plays   an  important   role    in  fear
conditioning.   Because norepinephrine  has such    a   powerful
effect, undoing learned fear    can be  an  intensive   process—
ask  anybody     suffering   from    post-traumatic  stress  disorder,
or  PTSD.
Milder   forms   of  stress  can     also    activate    many    of  the
same    pathways.   The “stress”    of  learning    a   new instrument,
solving  a   crossword   puzzle,     or  experiencing   novelty—
exploring    a   new     town,   or  going   on  a   walk    with    changing
scenery,     for     example—all     have    been    shown   to  increase
norepinephrine  in  the brain.  This    can be  very    beneficial, as
norepinephrine   helps   to  make    the     connections     between
neurons stronger.
                    
                      john hannent
                      (John Hannent)
                      
                    
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