individual  micronutrients. We’ve   coevolved   with    our food,
and  trying  to  optimize    our     infinitely  complex     bodies  by
cherry-picking   nutrients   may     be  the     ultimate    exercise    in
hubris. F-acids are the perfect case    in  point:  pharmaceutical
companies   have    been    trying  to  distill and extract purer   and
purer    concentrations  of  EPA     omega-3s    from    fish    to  create
super-potent     fish    oil,    but     they    don’t   always  show    the
expected     anti-inflammatory   benefit.    Could   this    be  because
these   super-delicate  yet powerful    furan   fats    are destroyed   in
manufacturing?  This    is  why we’re   always  in  favor   of  whole
foods    over    supplements—even    the     supplements     we
recommend!
ALA—The Plant Omega-3
I’ve    briefly mentioned   another common  omega-3:    plant-
based   alpha-linolenic acid,   or  ALA,    found   in  seeds   and nuts
like    flaxseeds,  chia    seeds,  and walnuts.    In  our bodies, ALA
needs   to  be  converted   to  DHA and EPA to  be  used,   but this
is   a   very    inefficient     process,    and     what    limited     ability     we
possess further declines    with    age.^26
Healthy  young   men     convert     an  estimated   8   percent     of
dietary ALA to  EPA,    and 0   to  4   percent to  DHA.    In  fact,   the
conversion   of  ALA     to  DHA     is  so  limited     in  men     that
consuming   more    ALA (from   flaxseed    oil,    for example)    may
not increase    DHA in  the brain   at  all.    Women,  on  the other
hand,    are     approximately   2.5     times   more    efficient   at
converting   ALA,    an  ability     thought     to  be  facilitated     by
estrogen     to  support     the     needs   of  future  childbearing.
