L
SUW; WOI); Gastrosis (f; JLH); Giardia (1; PR13:561); Gingivosis (f; JLH); Gout (f; DEP;
MPI); Hemorrhoid (f; MPI); Hepatosis (f; DEP; JLH); Hoarseness (f; DEP); Immunodepression
(1; PR13:561); Induration (f; JLH); Infection (1; KAP); Inflammation (1; MPI; WOI); Insomnia
(f; MPI; WOI); Ischiosis (f; HHB); Leprosy (f; WOI); Leukoderma (f; MPI); Lumbago (f;
DEP; KAB; MPI); Mastosis (f; JLH); Myalgia (f; WOI); Mycosis (f; KAP); Nervousness (f;
MPI; WOI); Nyctalopia (f; DEP); Ophthalmia (f; KAB); Pain (1; SKJ; WOI); Palsy (f; DEP;
KAP; MPI); Paralysis (f; HHB; KAB; SKJ); Paraplegia (f; DEP; KAB); Puerperium (f; SKJ);
Pulmonosis (f; DEP); Rheumatism (f; HHB; MPI); Salmonella (1; MPI); Sciatica (f; DEP;
KAB); Sclerosis (f; JLH); Snakebite (f; DEP); Sore Throat (f; JLH); Splenosis (f; KAB; MPI;
SKJ); Staphylococcus (1; MPI); Stomatosis (f; JLH); Swelling (f; DEP); Tetanus (f; DEP);
Thirst (f; SKJ); Tuberculosis (1; KAP; MPI); Uvulosis (f; JLH); Wart (f; JLH); Worm (1;
HHB; KAB; KAP; MPI).Dosages (Long Pepper) — No modern dosages uncovered. 1–2 g ground fruit could provide
biologically active levels of piperine. Old peppers are believed to be more medicinally active than
fresh peppers (DEP).Extracts (Long Pepper) — Alcoholic extracts of fruits and aqueous leaf extract active against
Escherichia coli and Micrococcus pyogenes. In human volunteers, 20 mg piperine increases
bioavailability of curcumin 20-fold (MAB). Long pepper may contain 2% piperine suggesting
that 1 gram of long pepper could increase availability of curcumin 20-fold. Milk extract effectively
reduced passive cutaneous anaphylaxis in rats. Ether extracts and fruits are decoction antiedemic
and antiinflammatory. Root powder at 100 mg/kg completely reduced fertility in rats on days 6
to 9 of pregnancy. 50% ethanolic extract is antispasmodic and hypoglycemic. N-isobutyl-deca-
trans2,trans4-dienamide active against Mycobacterium tuberculosis in vitro and in vivo ( = 20%
as potent as streptomycin). EO active against Bacillus cereus, B. subtilis, Escherichia coli,
Mycobacterium tuberculosis, Salmonella thypi, Sar. lutea Shigella boydi, S. dysenteriae, Staphy-
lococcus albus, S. aureus, and Vibrio cholera. EO fungicidal against Aspergillus flavus, Curvu-
laria lunata, Penicillium javanicum, P. striatum, and Trichoderma viridi. Oil anthelmintic to
Ascaris lumbricoides. Crude extracts (and piplartine) suppressed ciliary movements in frog
esophagus suggesting that it might suppress the cough reflex in humans (MPI). Piperine may be
used as an analeptic in morphine poisoning, in lieu of nalorphine, especially if analgesia is
desired (MPI).LOOSESTRIFE (Lysimachia vulgaris L.) +Activities (Loosestrife) — Antipyretic (f; EFS); Astringent (f; EFS; PNC); Expectorant (f; EFS;
PNC); Hemostat (f; EFS); Vulnerary (f; EFS).Indications (Loosestrife) — Bleeding (f; EFS; PH2); Diarrhea (f; EFS; HHB; PH2); Dysentery
(f; HHB; PH2); Epistaxis (f; PH2; PNC); Fever (f; EFS); Menorrhagia (f; PH2; PNC); Metrorrhagia
(f; PH2); Scurvy (f; PH2); Sore (f; EFS); Wound (f; PH2; PNC).Contraindications, Interactions, and Side Effects (Loosestrife) — Not covered (AHP). “Hazards
and/or side effects not known for proper therapeutic dosages” (PH2) (but PH2 designates no specific
quantified dosage! JAD).