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Indications (Shepherd’s Purse) — Arrhythmia (2; PHR); Bacteria (f; APA); Bleeding (1; APA;
BGB; FAD; PH2; PNC; SHT); Bruise (1; BGB; FAD); Burn (2; PHR; PH2); Calculus (f; PH2);
Cancer (1; JLH; PNC); Cancer, stomach (f; JLH); Cancer, uterus (f; JLH); Capillary Fragility (1;
CAN); Cardiopathy (2; PHR); Childbirth (1; FAD); Chyluria (f; BGB); Colic (f; CEB); Colorrhagia
(f; BGB); Constipation (f; APA); Cramp (f; DEM); Cystosis (f; APA; BGB; PH2); Dermatosis (f;
DEM); Diarrhea (f; APA; BGB; FAD); Dysentery (f; DEM; FAD); Dysmenorrhea (f; CAN; FAD;
PH2; SHT); Epistaxis (2; BGB; KOM; PH2; PIP); Fever (f; CEB; PNC); Fibroma (f; JLH); Gastrosis
(f; JLH); Headache (f; DEM; PHR; PH2); Hematemesis (f; APA); Hematuria (f; APA; BGB);
Hemorrhoid (f; APA; CEB); High Blood Pressure (2; APA; BGB; KOM); Inflammation (1; APA;
BGB; PH2; PNC); Leukorrhea (f; BGB); Low Blood Pressure (2; KOM); Menorrhagia (2; BGB;
CAN; KOM; FAD); Metrorrhagia (2; APA; KOM; PIP); Nervousness (1; PHR); Pain (f; CEB;
DEM); PMS (2; PHR; PH2); Poison Ivy (f; DEM); Pulmonorrhagia (f; BGB); Sore (f; CEB);
Stomachache (f; DEM); Tumor (1; PNC); Ulcer (1; APA; BGB; JLH; PNC); Uterosis (f; PH2);
UTI (f; APA; BGB); Water Retention (1; APA; FAD; PNC); Worm (f; DEM); Wound (2; BGB;
PHR; PH2).
Dosages (Shepherd’s Purse) — 1 tsp herb/cup water 2–4 ×/day (APA); 10–15 g herb/day (KOM;
PH2); 3–5 g herb:0.75 cup water for topical tea (KOM); 1–4 g dry herb, or in tea, 3 ×/day (CAN);
1–4 ml liquid herb extract (1:1 in 25% ethanol) 3 ×/day (CAN; PNC); 5–8 g fluid herb extract
(KOM; PIP); 1 tbsp herb extract 2–3 ×/day (APA); 20–30 drops herb tincture 2–3 ×/day (APA);
3–5 g/150 ml water (PIP); 10–15 g crude drug (SHT).
Contraindications, Interactions, and Side Effects (Shepherd’s Purse) — Class 2b. Emmenag-
ogue and uterotonic. Because of oxalates, patients with kidney stones and perhaps those with
endometriosis should avoid; large doses of extract may cause heart palpitations (AHP). Commission
E reports none known (KOM; PHR). “Hazards and/or side effects not known for proper therapeutic
dosages” (PH2). CAN reports isothiocyanates cause irritation. Reported to be abortifacient and to
affect menstrual cycle, its use in pregnancy and lactation is to be avoided. May interfere with blood
pressure, cardiac, sedative, and thyroid medications. Toxic doses induce difficult respirations (dys-
pnea), enlargement of pupils, paralysis of hind limbs, sedation, and death by respiratory paralysis.
Isothiocyanates may induce goiter (CAN). Seeds may blister skin (FAD). Parenteral application
only (KOM). LD50 = 1500 mg/kg ipr mus (CAN). Antitumor activity due to ubiquitous fumaric
acid (PNC).SHITAKE (Lentinus edodes) +++Activities (Shitake) — Antibacterial (1; X11137653); Antihepatosis (f; SKY); Antiseptic (1; APA);
Antiviral (1; WAM); Hypocholesterolemic (1; APA); Hypotensive (f; APA); Immunostimulant (1;
APA; SKY; WAM); Tonic (f; APA).
Indications (Shitake) — Anemia (f; APA); Bacteria (1; X11137653); Cancer (1; APA; SKY);
Cancer, breast (1; APA); Cancer, cervix (1; APA); Cancer, stomach (1; APA); Chemotherapy (f;
SKY); Cold (1; WAM); Diabetes (f; APA); Flu (1; WAM); Hepatosis (f; SKY); High Blood Pressure
(f; APA); High Cholesterol (1; APA); HIV (1; APA; SKY); Immunodepression (1; APA; SKY;
WAM); Virus (1; WAM).
Dosages (Shitake) — 1–3 (606 mg) capsules up to 3 ×/day (APA); 6–16 g mushroom/day (SKY);
extract 2–3 ×/day (SKY); 2–4 ml tincture (SKY).
Contraindications, Interactions, and Side Effects (Shitake) — Class 1 (AHP). No contraindi-
cations known (WAM). Safety during pregnancy not established (SKY). High dosages may induce
bloating and diarrhea (SKY). LEM used for recurrent stomach cancer in Japan, increasing survival
rate, especially in combination with chemotherapy.