S
Dosages (Sicklepod) — 1–3 g powdered seed (KAP); 5–15 ml seed tea (KAP).Contraindications, Interactions, and Side Effects (Sicklepod) — Class 2b, 2c, 2d (AHP).
Commission E and other sources report interaction of anthranoid laxatives (AEH). Anthranoid-
containing laxatives can be habit-forming. Some contain compounds suspected of being cytotoxic,
genotoxic, mutagenic, and even tumorigenic. Epidemiological studies in Germany reveal that
abusers of anthranoid laxatives have a three times higher rate of colon carcinoma.Extracts (Sicklepod) — Torachrysone, toralactone, aloe-emodin, rhein, and emodin were antibac-
terial against methicillin-resistant Staphylococcus. Antibacterial MIC = 2–64 μg/ml (X10478467);
antistaphylococcic MIC = 2–64 μg/ml (X10478467). Alaternin and two naphthopyrone glycosides,
nor-rubrofusarin-6-beta-D-glucoside (cassiaside) and rubrofusarin-6-D-gentiobioside were radical
scavengers. Chrysophanol, chryso-obtusin, aurantio-obtusin, cassiaside, and rubro-fusarin-gentio-
bioside demonstrated significant antimutagenic activity (X9063089). Seed extracts contain at least
five hepatoprotective compounds.SILVER VINE
(Actinidia polygama (Siebold & Zucc.) Maxim.) +Synonym: Trochostigma polygama Siebold & Zucc.Activities (Silver Vine) — Cardiotonic (f; CRC); Diuretic (f; CRC); Euphoriant (f; CRC); Hallu-
cinogen (f; CRC); Narcotic (f; CRC); Sedative (1; CRC); Tranquilizer (1; CRC).Indications (Silver Vine) — Colic (f; CRC); Insomnia (1; CRC); Nervousness (1; CRC); Rheu-
matism (f; CRC); Water Retention (f; CRC).SINICUICHI (Heimia salicifolia (Kunth) Link) +Activities (Sinicuichi) — Anticholinergic (1; CRC); Antidote (1; CRC); Antispasmodic (1; CRC);
Anxiolytic (1; CRC); Astringent (1; CRC); Depurative (f; CRC); Diaphoretic (f; CRC); Diuretic
(f; CRC); Emetic (f; CRC); Hallucinogen (1; CRC); Hemostat (f; CRC); Intoxicant (1; CRC);
Laxative (f; CRC); Myorelaxant (1; CRC); Narcotic (1; CRC); Poison (1; CRC); Psychomimetic
(1; CRC); Sedative (f; CRC); Tonic (f; CRC); Tranquilizer (1; CRC); Vasodilator (1; CRC);
Vulnerary (f; CRC).Indications (Sinicuichi) — Anxiety (1; CRC); Bleeding (f; CRC); Bronchosis (f; CRC); Consti-
pation (f; CRC); Cramp (1; CRC); Dysentery (f; CRC); Dyspepsia (f; CRC); Fever (f; CRC);
Insomnia (f; CRC); Nervousness (1; CRC); Sore (f; CRC); Syphilis (f; CRC); VD (f; CRC); Water
Retention (f; CRC).SKIRRET (Sium sisarum L.) ++Activities (Skirret) — Aperitif (f; PH2).
Indications (Skirret) — Anorexia (f; PH2); Dyspepsia (f; PH2); Salivation (f; HHB).
Contraindications, Interactions, and Side Effects (Skirret) — Not covered (AHP). “Hazards
and/or side effects not known for proper therapeutic dosages” (not given) (PH2). The danger comes
from confusing this with poisonous umbellifers (JAD).