seealsospecificinfec-
tions;Vaccines
Immunoconglutinins 141
Immunoelectrophoresis
122 – 1 23, 124
Immunofluorescence
125 – 1 28, 141 , 212
direct 125 – 1 26, 127
indirect 127 – 128
Immunogen 45 , 142
Immunoglobulins 48 – 50
classesof 4 9,50, 54 – 57
classswitching 54 – 56
functions 56
variabilitytypes 56
diversity52, 53 – 54
geneticorganization
53 – 54
structure 50 – 53
Fab52, 140
Fcfragment53, 140
hingeregion 141
hypervariableregion
141
seealsoAntibodies;IgA;
IgD;IgE;IgG;IgM
Immunologicalcelldeath
88, 90
Immunologicalmemory
94 – 99, 142
B-cellmemory 94 – 96
needfor 97
T-cellmemory 95 – 96 ,
9 8–9 9
Immunomodulators 207
Immunopathology 43 – 4 4,
103 – 105 , 108 – 115
typeI:IgE-triggered
anaphylaxis 108 – 109
typeII:cytotoxichu-
moralimmunere-
sponses 109 – 113
antibloodgroupanti-
bodyreactions
11 1–1 12
autoantibodyre-
sponses 110 – 111
typeIII:diseasescaused
byimmunecomplexes
11 3–1 14
typeIV:delayedtype,
cell-mediatedhyper-
sensitivity 98 – 99,
114 – 115
Immunoprecipitation
12 1–1 23
Immunoregulation
118 – 119
immunostimulation 119
immunosuppression 4 4,
120
tumorgrowthand 108
Immunotherapy 120
Immunotolerance 1 3, 4 4,
90 – 9 4, 144
B-celltolerance 93 – 94
T-celltolerance 90 – 93
central 90
complete,exhaustive
T-cellinduction
9 1–9 2
peripheral 90 – 91
T-cellindifference/ig-
norance 91
Impedins 7 , 11
Impetigo 651
In-PouchTestSystem 482
Inactivatedpoliovaccine
(IPV) 437
Incerta 477
Incidence26, 27
Inclusionconjunctivitis
336, 339
Incubationperiod9, 27
Infection 10
endogenous 10
exogenous 10
generalized 10
inapparent 10
latent 394
local 10
modeof 9
nosocomial 1 0, 342 – 346
sourcesof 30
spectrum 9
subclinical 10
InfectiondefensesseeDe-
fensemechanisms;Im-
munity
Infectiousdiseases 2 – 3, 10
clinicalsymptoms
1 5–1 8
fightagainst 31 – 34
exposureprophylaxis
31
immunizationpro-
phylaxis 31 – 34
legislation 31
seealsoDisinfection;
Sterilization
generalschemesof 101
seealsospecificdiseases
Infectiousmononucleosis
424
diagnosis 631 , 648
Inflammation 1 8, 113
Influenzaviruses 458 – 460
antigenstructure 459
antigenicshift 460
classification 459
clinicalpicture 459
diagnosis 459
cardiovascularsystem
647
eyeinfections 655
respiratorytract630,
631 , 632
epidemiology 460
pathogenesis 459
prevention 460
replication 458 – 459
structure 458
therapy 460
Insecta 60 6, 612 – 620
seealsospecificparasites
Insertionsequences(IS
elements) 17 3, 180
Instrumentdisinfection 41
Integrins 84
Integron 17 2, 179
Intercellularadhesion
molecule(ICAM) 529
Interferongamma-induci-
bleprotein(IP-10) 82
Interferon-stimulated
genes(ISG) 401
Interferons(IFNs)75, 7 6,
81 , 100 , 141
antiviralprotection
40 0–4 01
effectsof 40 0, 401
productionof 400 – 401
Interleukins(IL)75,
77 – 78, 80 – 81 , 10 0, 141
immunostimulation 119
Interstitialpneumonia 371
Intraperitonealabscess
643
Intron 142
Invasins 7 , 11 , 282
Invasionandspread 12
Invasivefactors 282
Invertedrepeats 180
Iodamoebabu ̈tschlii
504 – 505
Iodine 40
Ionizingradiation 38
Iraconazole 356
Iron,cumulationbybac-
terialcells 282
Isologous 142
Isoniazid 191
Isonicotinamides 191
Isopropanol 39
IsopropanolI 679
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Kayser, Medical Microbiology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.