Biology Questions and Answers
- For the enzymatic reaction
what is the effect of a
substance with the same
spatial conformation as an
enzymatic substrate? How is
this type of substance known?
Substances that “simulate” substrates
can bind to thenzymes thus blocking te activationhe true center of
substrates to bind to these enzymes and
paralyzing “fake substrates”the enzymatic are called reaction. enzymeSuch
inhibitors.
The binding of enzyme inhibitors to
enzymes can be reversiblirreversible. e or
Many medical drugs, for example, antibiotics, antivirals, antineoplastics,some
antihypertensives and even sildenafil
(trade name Viainhibitors that blgra), are ock enzyme activity.enzyme
- What is the action
mechanism of the antibiotic
penicillin?
Penicillin,doctor Alexan discovereder Flemind by the Scottishg in 1928, is a (^)
drug that infor the synthhibits enzymes nesis of peptidoglycans, aecessary (^)
constituent of the bacterial cell wall.
With the inhibition thpopulation stops growing because e bacterial (^) there
is no new cell wall formation.
Fleming won the Nobel prize in Medicinefor the discovery of penicillin.
- What is the action
mechanism of the
antiretroviral drugs called
protease inhibitors which are
used against HIV infection?
Protease antiretroviralinhibitors are som drugs used to treat HIe of the (^) V
infection. Protease is an enzyme
necessary foafter the synthr the assemblinesis of its proteins withing of HIV (^)
the host cell. The protease inhibitor
binds to enzyme blocking ththe activatione formation o center of thef the (^)
enzyme-substrate complex and the
enzyme activityreplication. thus impairing the viral
- What are allosteric
enzymes?
Allostericmore than one activation enzymes are those that hav center and toe (^)
which othregulators,er substances, bind. called allosteric
Allostericinhibitors or regulators can ballosteric activators.e allosteric The (^)
interactionenzyme and the allosteric between an allosteric inhibitor (^)
disallows the binding of the substrate to
the enzyme. The interaction bthe allosteric enzyme and the allostericetween (^)
activator allows the binding of the
substrateincreases the affinity of the enzyme for to the enzyme and sometimes
the substrate. This regulatory
phenomenon of the enzyme activitycalled allosterism. is
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