9 Scientific Research
at L.I.-11on uraemic pruritus. The results of the pruritus score
questionnaires demonstrated that only true acupuncture at L.I.-11
resulted in a significantly reduced pruritus lasting for a period of
three months. Uraemia levels remained unchanged. Che-yi et al,
Nephro Dial Transplant 2005
A German prospective, randomised, placebo-controlled, single-
blinded experimental trial (n22) investigated the effect of
L.I.-11on the phagocytic immune system. Based on laboratory
parameters, the activity of neutrophilswas significantly higher
in the study group. Karst et al, Complement Ther Med 2003
A Swedish prospective, non-randomised, placebo-controlled,
single-blinded experimental longitudinal trial investigated the
influence of electro-acupuncture at L.I.-11and L.I.-4on sym-
pathetic nerve activity and the pain threshold. Only electro-
acupuncture at L.I.-11 and L.I.-4 increased the pain threshold in
combination with increased sympathetic nerve activity. Knar-
dahl et al, Pain 1998
A Swedish prospective, randomised, placebo-controlled, single-
blinded trial (n58) investigated the effect of laser acupunc-
ture at L.I.-11and L.I.-12for lateral humeral epicondalgia
(tennis elbow)compared to laser application on the painful
area. There were no significant differences between the laser and
placebo treatments after the treatment period. Haker et al, Arch
Phys Med Rehabil 1991
L.I.-15A Taiwanese prospective, randomised, controlled, non-
blinded trial (n150) investigated the effect of electro-
acupuncture at L.I.-15, G.B.-21and Ex-UE jianneilingwith or
without regional nerve block (RNB) (stellate ganglion and
suprascapular plexus) for ‘frozen shoulder’ (adhesive capsuli-
tis). This was compared to RNB treatment alone. The combina-
tion of electro-acupuncture and RNB produced the most
significant reduction of pain and duration of pain relief as well
as improvement of range of motion. Lin et al, Acta Anaesthe-
siol Sin 1994
A Chinese prospective, randomised, controlled, non-blinded trial
(n63) investigated the effect of acupuncture at L.I.-15, L.I.-11,
L.I.-4, G.B.-30, G.B.-34, G.B.-37, LIV-3, G.B.-20, ST-25, ST-
40 , ST-36, SP-6and KID-3on symptoms of cerebral infarction
compared to the treatment with the calcium channel blocker vera-
pamil. The effectiveness in the acupuncture group was 94%, in the
verapamil group 84%. This difference is statistically significant.
However, the choice of a calcium channel blocker seems unusual
for this indication. Zou et al, Zhong Xi Yi Jie He Za Zhi 1990
L.I.- 12 1 cun
L.I.-11
L.I.-12L.I.-11; L.I.-10
A Chinese prospective, randomised, controlled trial (n64)
investigated the effect of electro-acupuncture at L.I.-12, T.B.-5,
G.B.-30and ST-36accompanied by medication for acute cere-
bral infarctionwith regard to the plasma and CSF somatostatin
levels. The control group received medication only. Both plasma
and CSF somatostatin levels increased significantly in the
acupuncture group. Zhang et al, J Tradit Chin Med 1999
A Chinese prospective, randomised, controlled trial (n64)
investigated the effect of electro-acupuncture at L.I.-12, T.B.-5,
G.B.-30and ST-36 on the plasma and CSF levels of VIP
(vasoactive intestinal peptide), somatostatin and pancreatic
polypeptide in patients with acute cerebral infarction. The
CSF VIP level dropped significantly while the plasma pancre-
atic polypeptide level increased significantly. In patients with a
good response both plasma and CSF somatostatin levels
increased significantly after acupuncture. Zhang et al, Zhen Ci
Yan Jiu 1996
Acromio
clavicular
joint
T.B.-14
L.I.-15
L.I.-20 Nasolabial groove
Midpoint of the lateral border
of the ala nasi
L.I.-20G.B.-14
A British prospective, randomised, controlled trial (n20)
investigated the effect of a 30 second massage at L.I.-20on
nasal airflowcompared to an untreated control group. Symp-
toms improved significantly in the massage group. Takeuchi
et al, Am J Rhinol 1999
Stomach channel
Infraorbitalmargin ST-2
ST-2G.B.-14
A prospective, non-randomised experimental trial (n33)
investigated the effect of acupuncture and electro-acupuncture at
ST-2, L.I.-4and ST-44on experimentally induced tooth pain.