of anxiety, depression, and various sleep disorders. St.
John’s wort is classified in the kingdom Plantae, divi-
sion Magnoliophyta, class Magnoliopsida, and order
Malpighiales. It is usually classified within the family
Hypericaceae but is also sometimes found within the
family Clusiaceae. Its genus isHypericum.
When St. John’s wort is used to refer to the herb
used to treat illnesses such as depression, it is the species
informally called Common St. John’s wort. Sometimes
also called Goat weed, hypericum, and Klamath weed,
it is the most plentiful species of St. John’s wort in the
world. It is classified as genus/speciesHypericum perfo-
ratum. As a perennial herb, St. John’s wort has the
ability to produce complicated underground creeping
stems, called rhizomes. Its above-ground stems are
straight and upright, branched within its upper half,
and able to grow up to one meter (three feet) in height.
BesidesH. perforatum, St. John’s wort can also refer
to the other species of St. John’s wort including scrubby
St. John’s wort (Hypericum prolificum), great St. John’s
wort (Hypericum ascyron), and Jerusalem star, or rose of
Sharon (Hypericum calycimum). In all, about 370 species
of the genusHypericumare found around the world.
Supposedly, the plant genus (Hypericum) was given
its name—from the Greek words hyper (above) and
eikon (picture)—in reference to John the Baptist, the
first centuryA.D. Jewish religious leader. The exact
reason for the naming is in question. Some of the
possible reasons for its name include: the blooming of
its yellow flowers in June around the time of John the
Baptist’s birth; the presence of the flower at a feast of
John the Baptist; and the hanging of the flower over
pictures in houses to supposedly protect against evil on
St. John’s day.
Purpose
St. John’s wort has been used for centuries to med-
ically treat mental disorders such as depression and
anxiety. The ancient Greek civilization is known to
have used it for this purpose. Early Native Americans
used it as anti-inflammatory (to control inflammation),
antiseptic (to control infection), and astringent (to
bring tissues together) medicines. The flowers of the
plant have been used to treat depression, anxiety, and
insomnia; sedate people; as a treatment for malaria;
and a balm for burns, insect bites, and wounds. In
recent history, parts of the plant have been used within
herbal tea.
However, it is also considered a poisonous weed in
over twenty countries. St. John’s wort is considered a
toxic weed that invades more productive plants and
flowers. When eaten by domesticated animals, such as
cows and horses, it can cause problems in the central
nervous system, abortion in pregnant females, and
even death.
Today, the flowers of the St. John’s wort
contains hypericin, a chemical that supposedly has anti-
inflammatory and antidepressant properties. TheHyper-
icumextract, which is obtained fromH. perforatumis
used in the United States as a popular herbal medicine
(alternative to standard medicine) for the treatment of
mild depression. In the United States, according to the
National Institutes of Health (NIH), St. John’s wort is
one of the leading herbal products sold. This sales volume
St. John’s wort flowers.(Photo Researchers, Inc. Reproduced
by permission.)
KEY TERMS
Anticoagulants—Blood thinners.
Antiseptic—Medicine used to control infection.
Astringent—Substance that brings tissues together.
Extract—A compound in which something has
been taken out so that it is now in a more purified
state.
Placebo—An inactive substance (such as a sugar
pill) used as a control in experiments.
Perennial—Reoccurring, as a plant that comes
back for more than one growing season.
Rhizome—An underground creeping stem.
St. John’s wort