ABDOMINAL AND GASTROINTESTINAL
EMERGENCIES
TABLE 11.9. Common Causes of Large Bowel Obstruction
ETIOLOGY PATHOPHYSIOLOGY DIAGNOSIS/TREATMENT
Colorectal cancer Most common cause of LBO; history Diagnosis can be made with contrast enema or
may reveal change in bowel habits, colonoscopy. CT may be helpful in evaluating extension
rectal bleeding, weight loss and metastases. Treatment in cases of LBO is resection
of involved segment.
Diverticulitis Second most common cause of LBO; CT is diagnostic.
infection of the walls of diverticuli leads Treatment is conservative and includes broad spectrum
to bowel edema and secondary obstruction; antibiotics, NPO, NGT decompression, and fluid,
second most frequent cause of large-bowel electrolyte repletion.
obstruction
Occurs in 10–25% of pts with
diverticuli; incidence increases with age.
Right-sided diverticular disease is more
common in pts of Asian and African descent.
Sigmoid volvulus Rotation of a segment of bowel on an axis AXR: A single distended loop of bowel is seen rising out
formed by its mesentery; older pts, of the pelvis. Contrast enema: A dilated bowel loop
bedridden pts, and those w/ psychiatric with bird’s beak shape. CT is also diagnostic.
illness taking anticholinergic medications Treatment: Decompression with a scope or rectal tube
are at risk for sigmoid volvulus; history of may be successful. Resection and fixation are indicated for
constipation unsuccessful attempts and strangulation.
Cecal volvulus Congenital defect in the peritoneum AXR or contrast enema is diagnostic: Distended ovoid
resulting in the twisting of the mobile cecum that takes a “coffee bean” shape.
segment of the cecum; most common in Treatment is surgical.
younger men and gravid females
Intussusception Proximal segment of bowel invaginates Contrast enema is diagnostic and therapeutic in
into more distal segment; primarily a 60–80% of cases
disease of children Diagnosis may also be made with abdominal ultrasound
or CT; unsuccessful reduction with enema or
evidence of perforation treated with operative resection
Acute colonic Seen in elderly patients hospitalized with CT is diagnostic; correct underlying precipitating
pseudo-obstruction severe illness; massive dilatation (>10 cm disorder. Initial conservative management with bowel
(Ogilvie syndrome) in diameter) usually of the cecum and right rest, hydration and correction of electrolyte
colon in the absence of a mechanical abnormalities; avoid medications that slow colonic
obstruction;often an underlying surgical motility; pharmacologic treatment with neostigmine or
disorder or precipitated by a medical colonoscopic decompression may be effective in cases
disorder that do not resolve with conservative management
Surgical intervention is reserved for refractory cases or cases
complicated by perforation.
■ Emergent surgical consultation is imperative as operative management
is often necessary. Management may vary depending on etiology. (See
Table 11.9.)
■ Antibiotic regimens include tazobactam-piperacillin, cefotetan, ertape-
nam, or combination of a fluoroquinolone and metronizadole.