OBSTETRICS AND GYNECOLOGY
602Trichomoniasis is almost
always an STD!DIAGNOSIS
■ Usually, visualization of the vagina allows a clinical diagnosis.
■ Confirm diagnosis based on the presence of pseudohyphae and spores
(“spaghetti and meatballs”) on wet mount exam with a 10% KOH prep.TREATMENT
Oral or intavaginal antifungals:
■ Clotrimazole 1% cream or miconazole 2% cream topically for 3–7 days
■ Fluconazole 150 mg PO ×one doseA 50-year-old female presents to the ED with the third visit in 2 months
for candida vulvovaginitis that seems resistant to treatment. What do you
want to check?
Accucheck to rule out underlying diabetes.TRICHOMONIASISCaused by Trichonomas vaginalis, a flagellated protozoan.SYMPTOMS/EXAM
■ Vaginal discharge, perineal itching, dysuria, spotting, and pelvic pain
■ Physical exam shows vaginal erythema and a frothy malodorous discharge.
■ Trichomoniasis is associated with premature rupture of membranes,
preterm delivery, and postpartum endometritis.DIFFERENTIAL
Bacterial vaginosis, candida vaginitis, pelvic inflammatory diseaseDIAGNOSIS
The presence of motile, pear-shaped, flagellated trichomonads on wet mount
(see Figure 12.5).TABLE 12.5. Vaginal DischargeBACTERIAL
DISCHARGE NORMAL CANDIDIASIS TRICHOMONIASIS VAGINOSISColor Clear/white White Green/yellow Gray/whitepH <4.5 <4.5 >5.0 >4.5Amine odor Negative Negative Positive Positive
with KOHWet mount Epithelial cells, WBC, spores, WBC, motile Few WBC,
lactobacilli pseudohyphae trichomonads clue cells