0071643192.pdf

LIDOCAINE

Used in the treatment of VT and VFib as an alternative to amiodarone

MECHANISM OFACTION

■ Class Ib antidysrhythmic

■ Blocks fast sodium channels →stabilization of membranes

DOSE

■ Adult: 1–1.5 mg/kg IV/IO, may be repeated at 0.5–0.75 mg/kg every

5–10 minutes if needed to max of 3 mg/kg

■ Pediatric: 1 mg/kg IV/IO to maximum dose of 100 mg

COMPLICATIONS

■ Hypotension, bradycardia with block, seizures

MAGNESIUM

Used in the treatment of VT or VFib associated with torsades de pointes and

prolonged QT

MECHANISM OFACTION

■ Improves serum magnesium levels →improved QT intervals

DOSE

■ Adult: 1–2 g diluted in 10 mL D 5 W IV/IO

■ Pediatric: 25–50 mg/kg IV/IO (maximum: 2 g)

COMPLICATIONS

■ Hypermagnesemia can cause decreased reflexes and at high levels decreased

respiratory drive, heart block, and asystole.

FIBRINOLYSIS

Administration of tissue plasminogen activator (tPA) may be considered in

patients with PEA due to suspected acute PE or MI. It is not indicated in

undifferentiated PEA.

DOSE

■ Adults: 100 mg IV over 15 minutes

MECHANISM OFACTION

■ Converts plasminogen →plasmin thereby activating fibrinolysis

GLUCOSE

May be a critical intervention in the pediatric population

RESUSCITATION

Excessive administration of

lidocaine may produce

neurological symptoms and

seizures.

Magnesium treats:

Torsades de pointes

Preeclampsia

Severe asthma