176.A 6-year-old boy is brought to the pediatrics clinic. His mother
reports that after her son eats peanut butter he complains of a tingling feel-
ing on the lips and in his mouth. After eating an ice cream cone at a local
dairy he developed an itchy rash with some swelling on his face. He also
had some difficulty in swallowing or breathing. This was followed by com-
plaints of “tummy pain” and cramping with diarrhea. During the patient’s
reaction, the cells in the accompanying micrograph, treated with fluorescein-
labeled antihuman immunoglobulin, would most likely be developing in
which organ where and would be producing which of the following?
276 Anatomy, Histology, and Cell Biology
a. Deep cortex of the lymph node, IgE
b. Germinal center of the lymph node, IgE
c. Germinal centers in the lymph node, IgA
d. Skin-associated lymphoid tissue, IgG
e. Perioarteriolar lymphoid sheath of the spleen, IgE
177.Where does immunoglobulin switching from IgM to IgG primarily
occur?
a. Bone marrow
b. Peripheral blood
c. Germinal centers
d. Thymus
e. Splenic red pulp