197.A woman presents with blisters on her back and buttocks (Figure A ).
She has autoantibodies to one of the cadherins that is distributed as shown
in Figure B. The cause of this disease is disruption of which of the following?
304 Anatomy, Histology, and Cell Biology
AB(Micrograph courtesy of Dr. Kristin M. Leiferman and the University of Utah, Department of
Dermatology site:http://uuhsc.utah.edu/derm/.)
a. Macula adherens
b. Hemidesmosome
c. Gap junction
d. Zonula occludens
e. Connections between the lamina densa and lamina rarae in the basal lamina