Gastrointestinal Tract and Glands 317
209.A young child presents with hepatomegaly and renomegaly, failure
to thrive, stunted growth, and hypoglycemia. A deficiency in glucose 6-
phosphatase is identified and the diagnosis is von Gierke disease. In the
liver, the structures labeled with the arrows in the accompanying transmis-
sion electron micrograph accumulate during this disease. What are the
labeled structures?
a. Chylomicra
b. Glycogen
c. Mitochondria
d. Peptide-containing secretory granules
e. Ribosomes