WORLD OF MICROBIOLOGY & IMMUNOLOGYx•
Introductionadvances in microbiology and immunology on history,
ethics, and society.- Bold-faced termsdirect the reader to related entries.
- “See also” referencesat the end of entries alert the
reader to related entries not specifically mentioned in
the body of the text.
•ASources Consultedsection lists the most worthwhile
print material and web sites we encountered in the com-
pilation of this volume. It is there for the inspired read-
er who wants more information on the people and dis-
coveries covered in this volume. - The Historical Chronologyincludes many of the sig-
nificant events in the advancement of microbiology and
immunology. The most current entries date from just
days before World of Microbiology and Immunology
went to press.
•Acomprehensive General Indexguides the reader to
topics and persons mentioned in the book. Bolded page
references refer the reader to the term’s full entry.
Although there is an important and fundamental link
between the composition and shape of biological molecules
and their functions in biological systems, a detailed under-
standing of biochemistry is neither assumed or required for
World of Microbiology and Immunology.Accordingly, stu-
dents and other readers should not be intimidated or deterred
by the complex names of biochemical molecules (especially
the names for particular proteins, enzymes, etc.). Where nec-
essary, sufficient information regarding chemical structure is
provided. If desired, more information can easily be obtained
from any basic chemistry or biochemistry reference.
Advisory Board
In compiling this edition we have been fortunate in being
able to rely upon the expertise and contributions of the follow-
ing scholars who served as academic and contributing advisors
for World of Microbiology and Immunology, and to them we
would like to express our sincere appreciation for their efforts to
ensure that World of Microbiology and Immunologycontains the
most accurate and timely information possible:Robert G. Best, Ph.D.
Director, Division of Genetics, Department of Obstetrics and
Gynecology
University of South Carolina School of Medicine
Columbia, South CarolinaAntonio Farina, M.D., Ph.D.
Visiting Professor, Department of Pathology and Laboratory
Medicine
Brown University School of Medicine
Providence, Rhode Island
Professor, Department of Embryology, Obstetrics, and
Gynecology
University of Bologna
Bologna, ItalyBrian D. Hoyle, Ph.D.
MicrobiologistMember, American Society for Microbiology and the
Canadian Society of Microbiologists
Nova Scotia, CanadaEric v.d. Luft, Ph.D., M.L.S.
Curator of Historical Collections
SUNY Upstate Medical University
Syracuse, New YorkDanila Morano, M.D.
University of Bologna
Bologna, ItalyJudyth Sassoon, Ph.D., ARCS
Department of Biology & Biochemistry
University of Bath
Bath, EnglandConstance K. Stein, Ph.D.
Director of Cytogenetics, Assistant Director of Molecular
Diagnostics
SUNY Upstate Medical University
Syracuse, New YorkAcknowledgments
In addition to our academic and contributing advisors, it
has been our privilege and honor to work with the following
contributing writers, and scientists: Sherri Chasin Calvo;
Sandra Galeotti, M.S.; Adrienne Wilmoth Lerner; Jill Liske,
M.Ed.; and Susan Thorpe-Vargas, Ph.D.
Many of the advisors for World of Microbiology and
Immunologyauthored specially commissioned articles within
their field of expertise. The editors would like to specifically
acknowledge the following contributing advisors for their spe-
cial contributions:Robert G. Best, Ph.D.
Immunodeficiency disease syndromes
Immunodeficiency diseases, geneticAntonio Farina, M.D., Ph.D.
Reproductive immunologyBrian D. Hoyle, Ph.D.
Anthrax, terrorist use of as a biological weaponEric v.d. Luft, Ph.D., M.L.S.
The biography of Dr. Harry Alfred FeldmanDanila Morano, M.D.
Rh and Rh incompatibilityJudyth Sassoon, Ph.D.
BSE and CJD disease, ethical issues and socio-economic
impactConstance K. Stein, Ph.D.
Genetic identification of microorganismsSusan Thorpe-Vargas, Ph.D
Immunology, nutritional aspectswomi_fm 5/6/03 1:34 PM Page x