Fundamentals of Medicinal Chemistry

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The value of 100r

2

is a measure of the percentage of the data that can

satisfactorily explained by the regression analysis. For example, a value of

r¼ 0 :90 indicates that 81 per cent of the results can be satisfactorily explained

by regression analysis using the parameters specified. It indicates that 19 per

cent of the data is not satisfactorily explained by these parameters and so

indicates that the use of an additional parameter(s) might give a more acceptable

account of the results. Suppose, for example, regression analysis using an extra

parameter gave a regression constant of 0.98. This shows that 96.04 per cent of

the data is now satisfactorily accounted for by the chosen parameters.

APPENDIX 6 REGRESSION ANALYSIS 251

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