many factors in addition to the decrease in RBC production was confirmed. The reduction in the
number of erythrocytes may also be linked to the activation of ineffective erythropoiesis, the
disruption of iron exchange, a shift in the metabolic status of the cells, and destabilization of
the cell membrane, which may lead to premature removal of erythrocytes from the
bloodstream.
PUBLICATION(S)
Gematologiya
Ivanova SM, Brazhe NA, Luneva OG, et al. Physical-chemical properties of plasma membrane
and function of erythrocytes of cosmonauts after long-term spaceflight. Acta Astronautica.
2011;68:1517-1522. doi: 10.1016/j.actaastro.2010.06.046.
Grigoriev AI, Ivanova SM, Morukov BV, Maksimov GV. Development of cell hypoxia induced by
factors of long-term spaceflight. Doklady Biochemistry and Biophysics. 2008;422:308-311. doi:
10.1134/S1607672908050141.
Grigoriev AI, Ivanova SM, Morukov BV, Maksimov GV. Onset of cellular hypoxia during long-
term spaceflight. Reports of the Academy of Sciences: Biochemistry, Biophysics, Molecular
Biology. 2008;422(6):823-826.
Ivanova SM, Maksimov GV, Morukov BV, et al. Role of the elasticity and permeability of the
plasma membrane of erythrocytes in regulating the effectiveness of hemoglobin oxygen
transport in humans after completion of a spaceflight. Aviakosmicheskaia i Ekologicheskaia
Meditsina (Aerospace and Environmental Medicine). 2007;41(2):41-44.
Morukov BV, Ivanova SM, Maksimov GV, et al. Investigation of the fluidity and permeability of
human erythrocyte plasma membrane and the efficacy of oxygen transfer by hemoglobin
during rehabilitation period after spaceflight. Journal of Gravitational Physiology.
2006;13(1):139-141.
Ivanova SM, Morukov BV, Labetskaya OI, Yarlikova YV, Levina AA, Kozinets GI.
Morphobiochemical research on the red blood cell system in primary crewmembers on the
International Space Station. Aviakosmicheskaia i Ekologicheskaia Meditsina (Aerospace and
Environmental Medicine). 2006;40(3):9-16.
Ivanova SM, Morukov BV, Labetskaya OI, Yarlikova YV, Levina AA, Shishkanova ZG. Red blood of
cosmonauts during missions aboard the International Space Station (ISS). Human Physiology.
2004;11(2):79-80.
Gematologiya Perfection
Ivanova SM, Morukov BV, Yarlikova YV, Labetskaya OI, Levina AA, Kozinets GI. Condition of red
blood cells in men during long-term antiorthostatic hypokinesia. Aviakosmicheskaya i
ekologicheskaya meditsina. 2005;39(6):17–22.